Yunnan University
Kunming 65009 1
Yunnan, China
Education and work experience
65438+September 0989-65438+July 0993, Department of Chemistry, Guangxi Normal University, Bachelor of Science.
65438+September 0993-65438+July 0996, Department of Chemistry, Guangxi Normal University, Master of Science, Organic Chemistry (Pharmaceutical Synthesis).
65438+August 0996-65438+February 0999, Department of Chemistry and Chemical Engineering, Guangxi Normal University, lecturer, organic chemistry.
1March 200, 9991June 5438+02, Ph.D. in phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences.
From June 2002 to June 2003, Kunming Institute of Botany, Chinese Academy of Sciences, assistant researcher, phytochemistry, natural product chemistry.
July 2003-February 2004, Kunming Institute of Botany, Chinese Academy of Sciences, associate researcher, phytochemistry, natural product chemistry.
From March 2004 to September 2004, she was a postdoctoral fellow at the School of Traditional Chinese Medicine, The Chinese University of Hong Kong, and was a secondary metabolite of higher fungi.
From June 5-438, 2004 to March 2006, he worked as a postdoctoral fellow in DAAD- Leibniz, Department of Bioorganic Chemistry, German Institute of Natural Products and Infectious Biology, focusing on microbial secondary metabolites.
April 2006-July 2007, Ph.D., Department of Biochemistry, Max Planck Institute of Chemical Ecology, Germany.
2007 165438+ 10-,Key Laboratory of Biological Resources Protection and Utilization, Yunnan University, researcher, secondary metabolites and functions.
Education and experience:
09/ 1989-07/ 1996, Department of Chemistry, China;
Master thesis "Synthesis of Allantoin"
07/ 1996-03/ 1999, lecturer in chemistry department of Guangxi Normal University, Guilin, China.
03/1999-12/2001,Ph.D. thesis of the State Key Laboratory of Phytochemistry and Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences.
01/June 2002/2003, Assistant Professor, State Key Laboratory of Phytochemistry and Plant Resources, Kunming Institute of Botany, Chinese Academy of Sciences.
07/2003- 12/2007, Associate Professor, State Key Laboratory of Phytochemistry and Plant Resources in Western China, Kunming Institute of Botany, Chinese Academy of Sciences.
03/2004-09/2004, postdoctoral fellow, School of Chinese Medicine, The Chinese University of Hong Kong,
10/2004-03/2006, post-doctoral Hans -Kn, Institute of Natural Products Research and Infectious Biology, Leibniz? Jenell Institute (HKI), Germany
04/2006-07/2007, postdoctoral fellow in Department of Biochemistry; Germany Jenmax Planck Chemical Ecology Biosynthesis/NMR Research Group
Professor, Laboratory of Biological Resources Protection and Utilization, Yunnan University, Kunming, China.
Awards:
2004. 10-2006.3, Postdoctoral Scholarship of German Academic Exchange Center (DAAD), Leibniz.
Main research directions:
Isolation and structural identification of natural products from microorganisms and plants
Chemical defense mechanism of nematode-trapping fungi
Biotransformation by using enzymes and microorganisms
Chemical interaction between plants and related microorganisms
Research interests:
Isolation and structural identification of natural products from microorganisms and plants in Yunnan
Biotransformation by using enzymes and microorganisms
Chemical defense mechanism of nematode-trapping fungi
Chemical interaction between plants and related microorganisms
Main scientific research projects undertaken:
At present, he undertakes or participates in research projects such as the National Natural Science Foundation and the Science and Technology Department of Yunnan Province.
Publications (2002-):
1. jason wu, Zhang Chunping, Zhu Chunyu, Wang, Guo Lei, Zhang, Niu Xiaomei *. Metabolites of carnivorous fungus Arthrobotrys entomopaga and their functions in the predation ability of fungi. Food chemistry 20 13, 6 1, 4 108? 4 1 13.(* correspondent)
2. Luo Sheng, Hua Jun, Niu Xiaomei, Liu Yan, Li Chun, Zhou Jing, Zhao, Li Sheng, defense diterpenoid lactone in Melaleuca, phytochemistry, 20 13, 86, 29-35.
3. Tan, Niu Xiaomei, Yang Guiying, Chloe Wang, Duan Yongxiang, Han Y, Zhang, Zhang CM. Quantitative determination of phytosterols in tobacco leaves by UPLC-MS/MS/ms.
4. Guo Pingping, Zhu Chunyu, Zhang Chunping, Chu, Wang, Zhang, Wu Dekang, Zhang, Niu Xiaomei *. Thermophilic bacteria lactone, an effective nematicidal hybrid metabolite of PKS-NRPS from thermophilic fungus Tallaro thermophilus, J Am Chem Soc, 20 12, 134(50), 20306-20309. (* correspondent)
5. Zhang, Tan, Wei Lingxia, Wang, Zhan Chunping, Wu DK, Zhu Chunyu, Zhang Y, Zhang, Niu Xiaomei. Morphological regulation metabolites of Arthropodium oligospora. Made in Japan, 2012,75 (7), 14 19- 1423. (* correspondent)
6. Wu Haiyan, Wang, Tan, Zhu Chunyu, Li Dongxing, Rui Huang, Zhang, Niu Xiaomei. Regulation of metabolites of Paecilomyces catenulata, an entomopathogenic fungus, on the growth of Helicoverpa armigera. Journal of Agricultural Food Chemistry, 2012,60 (22), 5604-5608. (* correspondent)
7. Luo Sheng, Liu Y, Hua J, Niu Xiaomei, Jing, Zhao X, Schneider B, Gershenzon J, Li Sheng, the role of the unique proline-benzoquinone pigment extracted from the colored nectar of the Coca-Cola tree of birds in bird scenic spots. Organic lites, 20 12, 14( 16), 4 146-4 149.
8. Shi Li, Nagy NE, Hammerbacher A, Krokene P, Niu Xiaomei, Gershenzon J, Schneider B. Localization of phenolic compounds in phloem parenchyma cells of Norwegian spruce, chemical biochemistry, 20 12, 13, 2707-27 13.
9. Guo Taiping, Tan, Wang, Wu Haiyan, Zhang Chunping, Niu Xiaomei *, Pan, Huang and Zhang. Talathermophilins were isolated from thermophilic fungus Talaromyces thermophilus YM3-4. J Nat Prod，20 1 1，74( 10)，2278-228 1。 (* correspondent)
10. Wei Lixin, Zhang, Tan, Chu, Li Ning, Xue, Wang, Niu Xiaomei, Zhang Y, Zhang. Arthrosporin A-C, a spore-bearing fungus from Arthrosporidium elegans, which preys on nematodes. J Nat Prod，20 1 1，74(6)， 1526- 1530。 (* correspondent)
1 1. Niu Xiaomei, Zhang. Arthrosporus oligospora: a model organism for understanding the interaction between fungi and nematodes. Mycology, 20 1 1, 2(2), 59-78.
12. Niu, Tian Yongxiang, Zhang Lei, Xu Xiaocheng, Niu Xiaomei, Zhang, Huang. The key virulence proteases Bace 16 and Bae 16 were overexpressed in Bacillus nematicidae B 16 to improve their nematicidal activity. J Mol Microb Biotechnology, 20 1 1, 2 1, 130- 137.
13. Yang Jike, Wang L, Ji Xiaoling, Feng Y, Li Xiaomei, Zou Chunling, Xu Jianping, Ren Y, Mi, Wu, Liu SQ, Liu Y, Huang, Wang HY, Niu Xiaomei, Li J, Liang LM, Luo Ji, Zhou W, Yu, Li GH, Liu. Genome and protein analysis of fungal oligospora robot provide insights into the formation of nematode traps. Plos Pathog，20 1 1，7，e 1002 179。
14. Yang Jike, Zhao, Liang Liming, Xia, Lei Liping, Niu Xiaomei, Zou Chunling, Zhang. Overexpression of epidermal degradation protease Ver 1 12 increased the nematicidal activity of Paecilomyces lilacinus. Appl Microbi ol Biot，20 1 1，89， 1895- 1903。
15. Li Guanghai, Yang, Zhao, Zheng, Luo, Sun, Niu Xiaomei, Zhang. Three new Acorane sesquiterpenes from Trichoderma spp. YMF 1.02647。 Phytochemistry Lite, 20 1 1, 4,86-88.
16. Chu, Niu Xiaomei *, Wang, Guo Taiping, Pan, Huang, Zhang. The putative biosynthetic intermediates of pentenoid indole alkaloids isolated from thermophilic fungus Talaromyces thermophilus. Organic Lite, 20 10, 12( 19), 4356-4359. (* correspondent)
17. Niu Xiaomei, Wang, Chu, Xue, Li Ning, Wei Lingxia, Mo Minghui, Zhang. Metabolites of Aurovertin-type nematicidal toxin from Puccinia chlamydospora, a parasitic fungus of root-knot nematodes. Journal of Agricultural Food Chemistry, 20 10/0,58 (2), 828-834.
18. Jerry Lee, Niu Xiaomei, Luo Qi, Xie Meijuan, Luo Shenghua, Zhou, Li Shenghua. A new type of polyesterified 3,4-creosote diterpene as antifeedant in Pieris elegans. Organic Lite, 20 10, 12 (10), 2426-2429.
19. Luo SH, Luo q, Niu Xiaomei, Xie meijuan, Zhao x, schneider b, Gehlsen j, Li SH. The glandular hairs of white silk disease contain defensive diterpenoids. Angew Chem Int Edit，20 10，49，447 1-4475。
20. Niu, Huang, Zhang Lei, Xu Jianping, Yang Deming, Wei Kebin, Niu Xiaomei, An, Bennett, Zou Chunling, Yang Jigang, Zhang. Trojan horse mechanism of pathogenic bacteria to nematodes. Proc National Academy of Sciences, 20 10, 107 (38),16631-kloc-0/6636.
2 1. Yang, Li Guanghua, Zhao, Zheng, Luo Shilin, Li Lei, Niu Xiaomei, Zhang. Nematicidal activity of Trichoderma spp. And separation of active compounds. Microbial life in the world. 20 10, 26, 2297-2302.
22. Mi, Yang Jigang, Ye Fengping, Gan Zhiwei, Wu Chaowei, Niu Xiaomei, Zou Chunling, Zhang. Cloning and high-level expression of chitinase gene Pcchi44 from chlamydospore shell, a potential pathogenic factor of nematodes. Process biochemistry, 20 10/0,45 (5), 8 10-8 14.
23. Terpenoids from Zhao Xiao, Zheng Guangwen, Niu Xiaomei, Li Wenqing, Wang Fusheng, Shi Li and Eupatorium adenophorum and their allelopathic effects on seed germination of Arabidopsis thaliana. JAgric food chemistry, 2009, 57, 478-482.
24. Niu XM, Dahse HM, Menzel KD, Lozak O, Walter G, Major L, Gray S, Satler I. Butyrolactone I derivatives from Aspergillus terrestris with unusual sulfate moiety, Journal of Natural Production, 2008,71,689-692.
25. Huang, He Jun, Niu Xiaomei, KD, Dahse HM, Grabley S, Fiedler HP, Sattler I, Hertweck C. Benzopyrene is a kind of polyketone metabolite of cytotoxic bacteria with benzo [a] pyrene type carbon ring system. Edited by Angew Chem Int, April 7, 2008, 1-5.
26. diastereoisomer of stilbene glycoside from Norwegian spruce bark. Phytochemistry, 2008, 69, 772-782.
27. Niu Xiaomei, Li SH, G? Rls H, Schollmeyer D, Hilliger M, Grabley S, Sattler I. Abyssomicin E, a highly functional polycyclic metabolite from Streptomyces species. Organic Lite, 2007, 9( 13), 2437-2440.
28. Niu Xiaomei, Li Sheng, Sun Gaoqing, Che CT. Two new wool steroids from resin ganoderma lucidum. Product Research of Asian Countries, 2007, Vol.9, No.7, pp.659-664..
29. Zhao Yan, Niu Xiaomei, Qian Liping, Liu, Zhao and Sun. Synthesis and cytotoxicity of some new calyxin B derivatives. European Journal of Medical Chemistry, 2007, 42(4), 494-502.
30. Niu Xiaomei, Li Sheng, Sun Gaoqing, Che CT. Isopentenoid phenols in ganoderma lucidum. National Production Magazine, 2006, 69(9), 1364- 1365.