Lu Su lost his father at an early age and was raised by his grandmother. He is not ambitious, generous to wealth, and likes martial arts riding and shooting. Therefore, he is quite famous in the local area. Yuan Shu proclaimed himself emperor in Shouchun (now Shouxian County, Anhui Province) and appointed him as the East Mayor. Lu Su resigned without authorization. Zhou Yu served as the director of Juchao (now Tongcheng, Anhui Province) and asked Lu Su to support the commissary. Lu Su generously showed him a big granary with 30,000 welcome grains. Zhou Yu was grateful, and finally.
Become bosom friends. In 200 AD, Lu Su joined Sun Quan on the recommendation of Zhou Yu. Sun Quan attached great importance to Lu Su, "sharing a bed with him" and discussing current affairs. Lu Su advised Sun Quan to "set foot in Jiangdong, see all the troubles in the world, ... and then build an emperor to build this world". Sun Quan admired his talent. During the Chibi War in 208 AD, Lu Su was a captain of Zanjun. He first proposed to Sun Quan the strategic policy of uniting Liu and Cao Cao, and sent envoys to Liu Bei to promote the alliance between Sun and Liu. In 2 10 AD, Zhou Yu died of illness, and Lu Su was appointed as a captain of Fenwu, and he was stationed in Jiangling. Later, he was transferred to Lukou, where he was awarded the position of Governor and General of Hanchang. Thorn (2 14) was transferred to General Hengjiang. 2 15 years, in Yiyang (now Yiyang City, Hunan Province). In 2 17, Lu Su died of illness.