For example, patients often ask, "Doctor, I think the instructions of Beijing No.0 antihypertensive drugs talk about the contraindications of Beijing No.0 antihypertensive drugs, saying that active digestive tract ulcers can't be eaten? I have suffered from gastric ulcer before. Can I still eat them? "
In fact, the taboo of Beijing No.0 antihypertensive drug in the instruction manual of Beijing No.0 antihypertensive drug can't be taken literally, so it's best to consult a doctor.
Regarding the zero contraindications of blood pressure reduction in Beijing-active digestive tract ulcer and depression, let's see what experts say.
Professor Su, the leader of the national key discipline (pharmacology) and chairman of the Ethics Committee of the Medical Science Committee of the Second Military Medical University, pointed out that Jiangya No.0 has four characteristics: obvious antihypertensive effect, stable and lasting effect, little side effect and low price. Taking Jiangya No.0 for a long time has protective effect on cardiovascular damage, kidney damage and brain cell damage caused by hypertension. In addition, we also verified the safety of two controversial points about Beijing's no.0 contraindication:
1. Active peptic ulcer
It is one of the contraindications, active digestive tract ulcer. Professor Feng from Su Ding emphasized that every tablet of Jiangya No.0 only contains 0. 1mg reserpine. According to the instructions of Beijing No.0 antihypertensive drug, the dosage of 1 tablet per day will not cause gastric ulcer, but taking 30 tablets per time will probably cause gastric ulcer. Therefore, oral low-dose reserpine will not cause ulcer, and it can be used safely. The therapeutic dose of antihypertensive 0 will not cause gastric ulcer.
2. Depression
The "ingredients" in the instructions of Beijing No.0 antihypertensive drug contain reserpine. Because reserpine has the risk of depression, Jiangya No.0 is controversial in this respect. Professor Su emphasized that every tablet of Jiangya No.0 only contains reserpine 0. 1mg, which is only 1/5 ~ 1/3 of the usual dosage of reserpine, so there is no risk of depression. Only a large dose of reserpine can lead to depression.
The same conclusion has been verified in many clinical trials conducted by Professor Sun Ningling from Peking University People's Hospital. Liu Jiaoshou, former president of the World Hypertension Union, pointed out that every tablet of Jiangya No.0 only contains 0. 1mg reserpine, so the safety of Jiangya No.0 can be guaranteed when the therapeutic dose is reduced.
Professor Sun Ningling also pointed out that long-term medication compliance of Jiangya No.0 is good and the curative effect is exact. Jiangya 0 is a long-acting antihypertensive drug, which can control blood pressure smoothly all day, no matter when it is taken.
Professor Hong Zhaoguang, the founder who participated in the research and development of Beijing Jiangya No.0, once said in an interview, "We often say that our medicine should be in line with international standards, but the only thing about Jiangya No.0 is that foreign countries are in line with China, and foreign countries learn from China." Jiangya No.0 has created a milestone in treating hypertension one by one. At that time, the prevention and treatment of hypertension all over the world were ladder drugs and single drugs. It usually takes 1 ~ 2 months for patients' blood pressure to reach the standard, but most patients can reach the standard after taking a tablet of 1 ~ 2 weeks every day. This is an innovative technology of China people.
However, the drug was marketed earlier, and the safety data could not be obtained from large-scale clinical trials according to modern drug marketing standards at the beginning of its birth. Theoretically, there are some contraindications. Clinicians should not absolutely understand the contraindications of Beijing antihypertensive drug No.0 in the instructions for Beijing antihypertensive drugs, but should combine the actual economic ability of patients to ensure the safe control of blood pressure.