Searching official website of the US Food and Drug Administration, we can find that Pidotimod oral liquid is an imported drug, made in Italy, with the date of issue of 20151February and the validity period of 20201February.
However, after investigating major foreign medical websites, Ji Lianmei found that the clinical efficacy and safety of this imported medicine from Italy were not clear in foreign medical research. According to Ji Lianmei's summary, the drug has four major problems.
Question 1: Researchers are mainly concentrated in China and a few European countries, such as Italian and Russian. The first two newly published articles belong to Dr. China. Unfortunately, it is still in the pre-clinical animal research stage, either chicken or mouse, which has no practical guiding significance for clinic.
Question 2: In 2065438+05, there was a study on the prevention of acute respiratory diseases in 57 healthy children who just entered kindergarten at the age of 3. However, randomized, double-blind placebo-controlled clinical studies showed that compared with placebo, pidotimod did not show statistically significant effect in preventing acute respiratory infection.
Question 3: To Ji Lianmei's great surprise, even in Cochrane, an authoritative evidence-based medicine library abroad, there is no literature to prove the safety and effectiveness of pidotimod in children, while the domestic research results are almost consistent and effective! These results show that pidotimod has a good preventive or therapeutic effect on recurrent respiratory tract infection, asthma, urinary system infection, gynecological infection, hepatitis C, and even non-infectious diseases such as vitiligo, tumor and allergic purpura, and it has become a panacea.
Question 4: Preschool children's autoimmune system is still mature, so don't be labeled as immunocompromised easily and take drugs at will. Except that vaccines can prevent diseases and improve children's immunity, there are no so-called drugs to improve children's immunity in mainstream countries in Europe and America.