Too little or too much sleep will increase the risk of heart disease. "This time, we have provided the strongest evidence to date that sleep time is a key factor for heart health and applies to everyone," said Celine Witt, correspondent of the study and assistant professor of comprehensive physiology at the University of Colorado at Boulder. In this study, the research team analyzed the genetic information, self-reported sleep habits and medical records of 46 1000 participants aged between 40 and 69 who had never suffered from heart disease in the British Biobank, and then followed them for 7 years. Compared with people who sleep 6-9 hours a night, people who sleep less than 6 hours are 20% more likely to suffer from heart disease during the study.
Those who slept more than 9 hours also increased their chances by 34%. When researchers only studied people with genetic predisposition to heart disease, they found that sleeping for 6-9 hours every night could reduce the risk of heart attack by 18%. "This is encouraging news," said Ijas Degrass of Harvard University, the first author of the study. No matter what your risk of hereditary heart disease is, healthy sleep will help reduce the risk. Just like a healthy diet, lifestyles such as non-smoking are also achievable. " Previous observational studies have shown that there is a correlation between sleep duration and myocardial infarction, but the causal contribution of the two and the potential of sleep to reduce the genetic susceptibility of coronary heart disease are still unclear. Many factors can affect heart health and sleep at the same time, which increases the difficulty of determining causality. In this new study, the researchers used a lot of data from British Biobank, combined with observation and genetic research, and asked questions in different ways.
After considering 30 factors such as body composition, activity, socio-economic status and mental health, they found that sleep time itself has an independent impact on the risk of heart attack. The longer people spend outside the 6-9-hour sleep range, the greater the risk of illness. For example, people who sleep 5 hours a night have a 52% higher risk of heart disease than those who sleep 7-8 hours, while those who sleep 65,438+00 hours a night have a double risk of heart disease. The researchers used Mendel's randomization method to observe the participants' gene maps to determine whether those who are genetically inclined to sleep for a short time are more likely to suffer from heart disease. They found that 27 genetic variants were related to lack of sleep and saw a similar pattern-short sleep time affected by heredity was a risk factor for heart attack.