Zhili College is one of the five strong foundation colleges established in 2020 in Tsinghua University to implement the national "Strong Foundation Plan". Zhili College, adhering to the long-standing spirit of science in Tsinghua and relying on the powerful teaching and scientific research resources of science in Tsinghua, undertakes the personnel training of mathematics and applied mathematics, physics, chemistry, biological science, information and computing science in the "Strong Foundation Plan".

Zhili College implements Tsinghua University's school-running philosophy of "shaping values, cultivating abilities and imparting knowledge", and takes "knowing what it is, managing it badly" as the development keynote of the college, and is committed to cultivating academic and industry leaders with family feelings, social responsibility and global vision. Explore, guide and cultivate every student's academic interest through personalized training scheme and tutorial system.

Through flexible training scheme, modular curriculum system and advanced academic training, the college provides students who are interested in exploring major basic science issues in the field of basic science with a solid scientific foundation, rich knowledge structure and profound humanistic quality, and helps students maintain their long-term curiosity about science, the innovative spirit of challenging major scientific issues and the ability to engage in emerging and interdisciplinary fields of basic science.