Dang Shengchun, Sha Xin, Cai Huazhong, Jiang Deli, Chen Min, Zhang Jianxin. Protective effect of disodium chlorophosphonate -SPIO liposome on liver injury in rats with severe acute pancreatitis and MRI evaluation. Chinese Journal of Hepatobiliary Surgery, 20 10,16 (11): 870-8746534. Zhang Jianxin. Research progress on the relationship between macrophages and acute pancreatitis. World chinese journal of digestology, 2008, 16(22): 2493-2496. The Party wins Spring, Mao, qu jianguo, Wang,. Changes of serum IL-2, IL- 10 and intestinal mucosal Fas in rats with severe acute pancreatitis. 15 (35): 3697-3702. Dang Shengchun, qu jianguo and Wang. Protective effect of ligustrazine on pancreatic and renal injury in acute necrotizing pancreatitis. Shandong Medicine, 2005; 45 (36): 16- 18. Dang Shengchun, qu jianguo and Wang. Intervention effect of ligustrazine on lung injury in acute necrotizing pancreatitis. West China Journal of Pharmacy, 2005; 20 (6): 483-486. The Party wins Chun, qu jianguo and Wang. Dynamic changes of serum TNF-a/IL- 10 in rats with acute necrotizing pancreatitis and the intervention of Salvia miltiorrhiza. China Journal of Pharmacy, 2006; 17 (3):182-184. Yin Kai, Dang Shengchun, Zhang Jianxin. Effect of myeloid cell trigger receptor-1 on intestinal barrier function in rats with severe acute pancreatitis. Chinese Journal of Emergency Medicine 20 1 1, 20 (8 Sha Xin, Cai Huazhong, Chen Min, Jiang Deli, Zhang Jianxin. Effect of disodium chlorophosphonate liposome on pancreatic injury in rats with severe acute pancreatitis. Journal of Jiangsu University (Medical Edition), 20 10/0,20 (2):104-107. Cai Huazhong, Yin, Cui. Party wins spring. Effect of chlorophosphonate liposome on apoptosis of peritoneal macrophages in rats with acute necrotizing pancreatitis. Chinese Journal of Hepatobiliary Surgery, 20 10, 16 (12): 943-946. Party wins spring, qu jianguo, Wang, Yin. Effect of disodium chlorophosphate liposome on apoptosis of alveolar macrophages in rats with pancreatitis. Chinese Journal of Hepatobiliary Surgery, 20 10,16 (3): 21215. Zhang Jianxin, Zhang Yong, Dang Shengchun, Sha Xin, Cai Huazhong, Chen Min, Jiang Deli. Effect of disodium chlorophosphate on liver injury in rats with acute necrotizing pancreatitis. Chinese Journal of Pancreatic Diseases, 20 10,10 (2): 99-10/. Zhang Jianxin, Sha Xin, Dang Shengchun, Zhang Yong, Cai Huazhong, Chen Min, Jiang Deli. Protective effect of disodium chlorophosphate liposome on renal injury in severe acute pancreatitis. Chinese Journal of Emergency Medicine, 2009,18 (11):1132-135. Cai Huazhong, Party. Zhang Jianxin. Effect of chlorophosphonate liposome on Kupffer cell apoptosis in rats with acute necrotizing pancreatitis. Chinese Journal of Pancreatic Diseases, 2009,9 (4): 259-261. , Yin,, Dang Shengchun,. Effect of disodium chlorophosphonate liposome on the function of peritoneal macrophages in rats. World chinese journal of digestology, 2009, 17(4): 347-35 1. Qin Xinyu, Dang Shengchun, qu jianguo, Wang. Dynamic changes of serum TNF-a/IL- 10 in rats with acute necrotizing pancreatitis. Shandong Medicine, 2005; 45 (36): 13- 15. qu jianguo, Dang Shengchun, Zhang Jianxin. Protective effect of ligustrazine on intestinal mucosa in rats with acute necrotizing pancreatitis. Journal of Jiangsu University (Medical Edition), 2006; 16 (5): 399-403. Wang, qu jianguo and Dang Shengchun. Effects of ligustrazine on microcirculation and inflammatory mediators in rats with acute necrotizing pancreatitis. Journal of Jiangsu University (Medical Edition), 2005; 15 (4): 288-290. Wang,, Dang Shengchun, qu jianguo. Protective effect of ligustrazine on gastric mucosal injury in acute necrotizing pancreatitis. Pharmaceutical information, 2005; 17: 1-4. qu jianguo, Zhang Jianxin, Cheng Guozhuo, Yang Jiahong, Xie Rong, Dang Shengchun. Experimental study on the correlation between gastric mucosal ischemia and inflammatory mediators in acute necrotizing pancreatitis. Journal of Hepatobiliary Surgery, 2003; 11(01): 65-66. Zhang Jianxin, Qu Jianguo, Dang Shengchun. The role of salvia miltiorrhiza in non-surgical treatment of severe acute pancreatitis. Journal of Jiangsu University (Medical Edition) G, 2004; 14 (5) 406-407,409. qu jianguo, Fan Xin, Dang Shengchun, Wang Ying, Zhang Jianxin. Role and mechanism of interleukin 1 receptor antagonist in acute pancreatitis. Guangdong medical, 2008; 29 (2): 228-229. Yang Jiahong, Dang Shengchun, Zhang Jianxin. Relationship between operative timing and postoperative complications in severe acute pancreatitis. Shandong Medicine 2008,4 (43):1-3 Sun Kang, Dang Shengchun, Huang Runsheng, Zhang Jianxin. Etiology and treatment of post-cholecystectomy syndrome. Shandong medicine 2065438.2002220650 (10): 40-41. The mechanism of multiple organ damage and the intervention effect of salvia miltiorrhiza won the second prize of Zhenjiang Science and Technology Progress in 2003. 2. Research on the mechanism and treatment of renal damage caused by acute necrotizing pancreatitis won the second prize of Zhenjiang Science and Technology Progress Award in 2005. 3. Intervention effect of ligustrazine on multiple organ damage in acute pancreatitis, third prize of Zhenjiang Science and Technology Progress Award in 2007. 4. The experimental study on the correlation between Fas/FasL-mediated pancreatic cell apoptosis and TH 1/TH2 deviation in severe acute pancreatitis won the second prize of Zhenjiang Science and Technology Progress Award in 2009. 5. The mechanism of gastrointestinal mucosal injury during 5.ANP and the intervention effect of ligustrazine passed the appraisal of Zhenjiang scientific and technological achievements in 2008. 6. The basic and clinical application research of high-field magnetic resonance in the diagnosis and resectability analysis of pancreatic cancer won the second prize of Zhenjiang Science and Technology Progress in 2009. Patent 1. Preparation method of magnetic disodium chlorophosphonate liposome Chen Min: Li Di; Xie; Party wins spring; Zhang Jianxin; Jiang Deli; Major scientific and technological project of Huang: 1) National Natural Science Research Foundation, Effect of intestinal macrophage TREM- 1 on intestinal mucosal barrier function during SAP, 2011.1-2013./kloc-0. Experimental Study on MR Evaluation and Treatment of SAP Multiple Organ Dysfunction Based on Nano-SPIO, 2008.01-2012,300,000 (Director Zhang Jianxin,) 3) Jiangsu Natural Science Research Fund, Experimental Study on MR Evaluation and Treatment of SAP Multiple Organ Dysfunction Based on Nano-SPIO, 2007. 1-2009. 12,70, 000 (application of SPECT based on nano-99 TCM- chlorophosphonate in the treatment and evaluation of severe acute pancreatitis 2008.05438+0-2010.12,60,000 yuan (seconds) 6) Zhenjiang medical key talent project: TLR-4 signal transduction and TH/kloc in severe acute pancreatitis.