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Why is the human body allergic?
Gail & Combs classified allergic reactions into four types. Type I is what we usually call acute or immediate allergic reaction, such as anaphylactic shock, acute urticaria, allergic rhinitis, allergic asthma, etc., which is more related to type E allergic reaction. Type ⅳ is a delayed allergic reaction. It is usually related to chronic recurrent urticaria and contact dermatitis. , and is related to type ⅳ allergic reaction. Then types ⅱ and ⅲ are mainly related to autoimmune diseases in our internal organs. At 1967, it was a landmark day, and a very important immunoglobulin E~IgE was isolated from the serum of Japanese hay fever patients. This is of great significance to reveal the mechanism of allergic reaction.

We say that allergic reaction is a kind of hypersensitivity. Our body is over-immune to foreign substances, especially protein and glycoprotein. We can understand allergy as an allergic mechanism or a pathological process.

As far as the current research results are concerned, the pathogenesis of many diseases may be related to allergic reactions.

Allergic reaction is a very large range, it is a phenomenon, a mechanism and a pathological process.

But allergic reaction is a clinical subject, and the content of clinical research at present is only a part of allergic reaction. At present, only a few general hospitals have allergy departments, or allergy departments and allergy clinics. However, there are still many hospitals, so these allergic diseases should be dispersed to many professional clinics, such as respiratory department, dermatology department, otolaryngology department and ophthalmology department. Children will come into contact with children with allergic symptoms or allergic diseases when they go to pediatrics, even in children's health care and preventive health care.

We say that allergic reaction is a kind of hypersensitivity. Our body is over-immune to foreign substances, especially protein and glycoprotein. We can understand allergy as an allergic mechanism or a pathological process.

We say that allergic reaction is a kind of hypersensitivity. Our body is over-immune to foreign substances, especially protein and glycoprotein. We can understand allergy as an allergic mechanism or a pathological process.

As far as the current research results are concerned, the pathogenesis of many diseases may be related to allergic reactions.

Allergic reaction is a very large range, it is a phenomenon, a mechanism and a pathological process.

But allergic reaction is a clinical subject, and the content of clinical research at present is only a part of allergic reaction. At present, only a few general hospitals have allergy departments, or allergy departments and allergy clinics. However, there are still many hospitals, so these allergic diseases should be dispersed to many professional clinics, such as respiratory department, dermatology department, otolaryngology department and ophthalmology department. Children will come into contact with children with allergic symptoms or allergic diseases when they go to pediatrics, even in children's health care and preventive health care.

Allergic diseases have a certain family genetic tendency, and are not hereditary diseases in the traditional sense. It just means that when one or both parents have allergic diseases, the probability of your baby suffering from allergic diseases is significantly higher than that of those children who have no genetic history.

If both parents have no allergic diseases, then the probability of their baby suffering from allergic diseases is only 10~ 15.

If one parent is allergic or suffers from allergic diseases, the probability of their baby suffering from allergic diseases will increase to 20~40.

If both parents are allergic or have allergic diseases, the probability of the baby getting sick will greatly increase to 50~80.

In particular, this allergic dermatitis is also called eczema, which has obvious maternal genetic tendency. In the process of children's allergy, their diseases have typical age characteristics.

Allergic diseases in children are different from those in adults. We usually say that children are not miniature adults. The growth of children is not only the growth of the body, but also the development of various physiological functions.

Therefore, allergic diseases in children are closely related to age. We say that many of their diseases have obvious age characteristics in the process of children's allergy. After the child is born, this allergic disease begins with atopic dermatitis, eczema, and is often accompanied by gastrointestinal allergies or allergic bowel diseases or food allergies. With the increase of age, these symptoms related to eczema and food allergies can be gradually alleviated.

In preschool, with the increase of age, the allergic symptoms of children's respiratory tract will gradually become obvious, especially the asthma of preschool children will reach the peak. This phenomenon, if the child is accompanied by a family genetic tendency, the probability of its persistence will also increase significantly.

With the growth of children's age, the prevalence of allergic rhinitis in children will reach its peak at school age. For this part of the children with family genetic tendency, it may be accompanied by life.

So we say that children's allergic process has obvious age characteristics.

Some symptoms can be replaced, and some symptoms may be alleviated.

Therefore, early and timely intervention in his allergic process can significantly reduce the risk and severity of his subsequent allergic diseases. The incidence of allergic diseases in children in China has risen sharply, and the allergic diseases in children in China have also shown an obvious upward trend. From 1999 to 2009, the food allergy of children aged 0-2 in Chongqing doubled in 10.

From 2002 to 20 12, infant eczema in Shanghai increased by 10 times.

The incidence of asthma among urban children in China has also doubled.

Therefore, it is urgent to standardize the diagnosis, treatment and management of allergic diseases in children in China.

Doctors in the allergic reaction discipline in China have also done a lot of epidemiological investigations, and the survey results show that:

About 40% parents of 0-2 year-old babies report that their children have or are suffering from allergic diseases. The total prevalence rate of allergic diseases in infants aged 0~2 years was 12.3%. The incidence of allergic diseases in children of different ages is completely different. Within 6 months, the incidence of allergic diseases in children of different ages was high, with the prevalence rate of 19.6%, mainly manifested as itchy skin, eye and nose symptoms and gastrointestinal symptoms.

Prevalence of five symptoms of allergic diseases in infants aged 0-24 months;

Rash and itching accounted for 8.5%, eye and nose symptoms accounted for 3.3%, wheezing accounted for 0.3%, gastrointestinal symptoms accounted for 2.0%, and lip symptoms accounted for 0.5%. The cumulative prevalence rate and prevalence rate of children's asthma in the National Children's Asthma Cooperation Group showed a significant upward trend in 1990, 2000 and 20 10.

During this investigation, we also found a very interesting phenomenon, that is, in areas with high degree of industrialization and urbanization, the incidence of asthma in children with allergic diseases is high.

The incidence of asthma in children in Northeast China is the lowest, and that in North China is the highest, so the highest incidence in cities is Shanghai. Every year when pollen drifts, it is also the saddest time for children with allergic rhinitis. Whether it is spring pollen or autumn pollen, for these children, it is tantamount to a high risk and a disaster. In recent years, the prevalence of allergic rhinitis in children in China has increased significantly compared with the past. According to the survey, as many as 52.7% of the children are moderately persistent and 12.2% are moderately intermittent. For the reasons of allergic reaction, we are constantly exploring and studying, and the related research on allergic reaction in China really lags behind that in developed countries. We admit our backwardness, but we are also bravely catching up.

In the past 20 years of continuous exploration and research, experts, scholars and clinicians in the field of allergic reaction in China have also done a lot of research work.

We have successively issued Evidence-based Recommendations for Diagnosis and Treatment of Infant Milk Protein Allergy in China and Guidelines for Diagnosis and Prevention of Asthma in Children in China. And we are constantly revising and perfecting it. "Expert Consensus on Diagnosis and Treatment of Children's Allergic Rhinitis" can also better guide our clinical frontline doctors and standardize diagnosis and treatment. In the treatment of allergic rhinitis, immunotherapy can effectively block the pathogenesis of allergic diseases. At present, more and more hospitals are also carrying out standardized desensitization treatment. I believe many of our parents are worried about their children's persistent chronic cough and turn to see a doctor. Therefore, the correct diagnosis and standardized treatment of chronic cough is also one of the responsibilities of our allergic reaction doctors.