Bioinformatics is a comprehensive subject. It involves mathematics, biology and computers. But in my opinion, the basic needs of computers are not very high, but the key is to have good biological knowledge, including genetics, biochemistry, developmental biology, molecular biology, plant physiology, etc. That is to say, we need to meet such a requirement: when analyzing data, we can evaluate all kinds of analysis results biologically and give the best analysis strategy. At the same time, we should also have a skilled mathematical foundation, including statistics and topology, so as to transform the problems to be analyzed into computable models and finally give the implementation plan.

Personally, because bioinformatics is a very large field, the key is to determine your own research direction. For example, bioinformatics oriented to correlation analysis should master various statistical analysis methods of correlation analysis, have strong data management ability and good enough sequence analysis ability (this is the basis for mutation search and analysis).