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[Research on Biology, Microbiology and Fungi] Microbiology paper "Study on Enterococcus Infection" (full format)
[Research on Biology, Microbiology and Fungi] Microbiology paper "Study on Enterococcus Infection" (full format)
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Chen Xin Microbiology Course Thesis. File (33KB)
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Treat enterococcus infection
data description
[Information Introduction]
Enterococcus is an important pathogen of nosocomial infection, which can not only cause urinary tract infection, skin and soft tissue infection, but also cause life-threatening abdominal infection, sepsis, pericarditis and meningitis. Because of its inherent drug resistance, it is difficult to treat infection. Enterococcus can only be infected if it colonizes in the host tissue, resists the nonspecific and immune defense mechanism of the body and causes pathological changes. This article reviews the biological characteristics, clinical manifestations, status, pathogenicity, drug resistance and treatment of enterococci in hospital infection.
[content]
Biological characteristics and classification of enterococci
Clinical manifestations of enterococcus infection
Status of Enterococcus in Hospital Infection
Pathogenicity of enterococci
Drug resistance of enterococci
Treatment of enterococcus infection
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[Original]
Biological characteristics and classification of enterococcus 1
Enterococci are round or oval Gram-positive cocci arranged in chains, without spores and flagella, and are aerobic or facultative anaerobic bacteria. This strain needs high nutrition and grows well on the medium containing serum. When cultured at 37℃ 18 hours, round colonies with gray, opaque, smooth surface and diameter of 0.5 ~ 1 mm can be formed, and different strains show different hemolysis phenomena. The remarkable difference from congenital streptococcus is that the strain can tolerate high salt and bile medium in biochemical reaction and has innate resistance to many antibacterial drugs.
According to the characteristics of carbohydrate utilization, enterococci can be divided into three categories: the first category is represented by avian enterococci; The second group used Enterococcus faecalis. Including Enterococcus faecalis, etc. ; The third category is E.coli. Duchenne, among which Enterococcus faecalis and Enterococcus faecalis are the most harmful pathogens to human beings. Enterococcus faecalis accounts for 85% ~ 95%, Enterococcus urosus accounts for 5% ~ 10%, and the rest are Enterococcus orientalis and other enterococci.
Clinical manifestations of enterococcus infection
2. 1 urinary tract infection
Urinary tract infection is the most common infection caused by Enterococcus faecalis, and most of them are nosocomial infections. It is reported that 16% of nosocomial urinary tract infections are caused by enterococci, which is second only to Escherichia coli [1]. Its occurrence is mostly related to indwelling catheter, operation of other instruments and abnormal urinary tract structure [3]. The common manifestations are cystitis and pyelonephritis, and a few are perirenal abscess.
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[reference]
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[2] R.E. Buchanan, N.E. Gibbons, etc., Berger's Handbook of Bacterial Identification, 8th edition, 1 edition. Beijing Science Press. 1984, 12.
Chen Dan. Advances in biochemistry and biophysics.1998,25 (2):140-143.
Song Shuishan, Zhao Zhanliang, Wang Lijie, et al. Bacterial quorum sensing mechanism and pathogenicity of animal and plant pathogens. journal of the hebei academy of sciences. Volume 20, No.2, May 2003.
[5]Moellering Jr PC。 Clinical infection dis.1992; 14: 1 173- 1 178
[6] Microbiology Education and Research Network