Change the obvious negation into the negation that may be found. First of all, significance is an index used to judge whether a factor has a significant influence on the experimental results. If the significance value changes from negative to positive, it will change the interpretation of the experimental results and affect the authenticity and credibility of the data. Secondly, many academic publications and databases will double-check the data. If abnormal changes or unreasonable data are found, they may be questioned or refused to publish. Therefore, it is suggested that in academic research, we should abide by academic integrity and moral norms, maintain a true, objective and fair attitude, and do not tamper with data or engage in other improper acts.