The prevention and control of plant soil-borne diseases, vascular bundle diseases and systemic diseases show unique advantages. These endophytic bacteria colonize in plants and are not easily affected by the external environment and can last for a long time. Moreover, many endophytic bacteria have biological functions such as nitrogen fixation, growth promotion and drought resistance, and have good development and utilization prospects. At present, many endophytic bacteria have been screened from rice, cotton, corn, potato and other crops, which have good control effect on plant diseases. However, there is relatively little research on endophytic bacteria in solanaceae crops. According to the main diseases of crops, more than 100 strains were isolated from tobacco, tomato, eggplant and pepper, which had strong antagonistic effects on plant pathogens such as tomato bacterial wilt, cucumber Fusarium wilt and rice bacterial blight. Endophytic bacteria with good growth promotion effect on tomato, inhibition effect on Phytophthora capsici and prevention and treatment effect on postharvest fruit blight of pepper +6 tested strains: Phytophthora capsici.