PDT acts on choroidal capillary network, causing embolism, thus preventing leakage caused by abnormal vascular permeability, which is beneficial to the treatment of mesoplasm. However, this therapy is not aimed at the diseased choroidal blood vessels, which may cause damage to normal choroidal tissue or retina. In addition, the price is more expensive.

Laser therapy has been widely used, but it will cause some damage to the retina (laser spot) and has the advantage of low price, but it is not suitable for the media with leakage near the macular area and chronic media with extensive leakage.

Compound anisodine injection has been widely used in recent years because of its good curative effect and relatively non-invasive.