Mbth ibuprofen, Perofen, Andean, Buedon, Brufen, Modin, Fenbid, Meifen.
Indications The analgesic and anti-inflammatory mechanism of this product is not completely clear, and it may play a role in local inflammatory tissues by inhibiting the synthesis of prostaglandin or other irritating transmitters. The product is suitable for relieving fever and moderate pain, such as arthritis, neuralgia, myalgia, headache, migraine, dysmenorrhea, toothache, cold and flu. For rheumatoid arthritis, its anti-inflammatory, analgesic and antipyretic effects are similar to those of acetylsalicylic acid and phenylbutazone, but better than acetaminophen. When patients can't tolerate acetylsalicylic acid, phenylbutazone, etc., this product can be tried. There was no obvious effect on hemogram and renal function.
Administration and dosage: 200 mg for adults each time, 1 ~ 3 times, with a maximum of 800mg； per day; The sustained-release agent can be 300 mg each time, 1 ~ 2 times a day. Children 65438+ 0 ~ 3 times a day, 1 under 20 ~ 30mg； each time; 1 ~ 3 years old 60mg； each time; 4 ~ 6 years old, each time100 mg; 7 ~ 9 years old150mg; 10 ~ 12 years old every time180 mg; 65438+200 mg each time over 02 years old. External use: 5%, 3 times a day.
Adverse reactions occasionally include mild dyspepsia, rash, gastrointestinal ulcer and bleeding, and elevated transaminase.
Precautions (1) Those who are allergic to aspirin or other non-steroidal anti-inflammatory drugs have a cross-allergic reaction to this product. (2) Pregnant women and lactating women should use it with caution. (3) Use with caution in patients with hemorrhagic diseases such as asthma, cardiac insufficiency, hypertension, hemophilia, digestive tract ulcer and renal insufficiency.
Contraindications (1) are prohibited for people who are seriously allergic to aspirin or other steroid drugs. (2) Patients with nasal polyp syndrome and angioedema are prohibited.
Drug Interaction (1) Drinking alcohol and using it with other NSAIDs will increase gastrointestinal side effects and also cause the risk of ulcer. (2) When combined with aspirin or other salicylic acid drugs, it can not increase the curative effect, but the incidence of gastrointestinal side effects and bleeding tendency increase. (3) Combined with anticoagulant, it increases the risk of bleeding. (4) This product can enhance the effect of antidiabetic drugs; Reduce the antihypertensive effect of antihypertensive drugs; Similar to corticosteroids, it can obviously slow down inflammatory symptoms. (5) It should not be combined with methotrexate to prevent poisoning. (6) When combined with probenecid, verapamil and nifedipine, attention should be paid to reducing the dosage; When using with digoxin, pay attention to adjust the dose of digoxin.
Administration and dosage: 200 mg for adults each time, 1 ~ 3 times, with a maximum of 800mg； per day; The sustained-release agent can be 300 mg each time, 1 ~ 2 times a day. Children 65438+ 0 ~ 3 times a day, 1 under 20 ~ 30mg； each time; 1 ~ 3 years old 60mg； each time; 4 ~ 6 years old, each time100 mg; 7 ~ 9 years old150mg; 10 ~ 12 years old every time180 mg; 65438+200 mg each time over 02 years old. External use: 5%, 3 times a day.
Specification tablets: 100mg, 200mg each. Sustained release capsule: 0.3g.. Liniment: 2.5g (50ml).
2. Mei Lin, deputy chief physician. Male, born in March, 1933, from Muyang, Jiangsu. ** * party member. 1947- 1954 worked in military medical schools and hospitals; 1954- 1957 graduated from the medical department of Jiangsu Health Cadre School; From 65438 to 0958, he worked in Nanjing Infectious Disease Hospital and Zhongfu Hospital successively. Main achievements: Mainly engaged in internal medicine and infectious diseases. Engaged in infectious diseases for more than 30 years and accumulated rich clinical experience. He took the lead in creating near infrared information to treat chronic hepatitis in Jiangsu Province. 1987 participated in Changchun International Hepatology Conference and won the Excellent Paper Award. 1989 cooperated with Shanghai Changzheng Hospital to treat chronic hepatitis with mushroom multi-mineral liposome, and won the first prize of scientific and technological progress of the whole army for its scientific research achievements. Since 1990, more than 50 cases of high jaundice hepatitis and chronic cholestatic hepatitis have been treated by hyperbaric oxygen in Jiangsu Province, and this achievement won the second prize of Nanjing Science and Technology Progress Award. He has published more than 20 scientific research papers in Chinese Journal of Physiotherapy, Journal of Clinical Internal Medicine and Jiangsu Medicine. China published the paper "Pregnancy-induced hypertension complicated with severe coma of yellow croaker 1 case" (Journal of Practical Obstetrics and Gynecology 1987 < 5 >).
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