Qiao Yangxian, male, from jianhu county, Yancheng, Qiao Bingyizi, Han nationality, was a teacher and graduated from Shanghai Health School. Chief physician of Shanghai Huadong Hospital. His father Qiao Yubing has three sons and a middle-aged son Qiao Yangxian. Under the cultivation and education of Qiao Bing, everyone has made achievements. Adopted son Qiao Yangxian, a national famous doctor. He once served as the third and fourth director of Shanghai Traditional Chinese Medicine Association, member of Geriatrics Society of Shanghai Chinese Medical Association, member of the first and second people's congresses and district committees of Zhabei District, member of the first and second directors of District Health Workers Association, member of Jing 'an Medical Accident Appraisal Committee, and member of the Expert Advisory Committee of Chinese Medicine Hospital.
Chinese name: Qiao Yangxian.
Nationality: China.
Ethnic group: Han nationality
Place of Birth: jianhu county, Yancheng
Date of birth: 19 14
Date of death: 2004
Occupation: doctor
Graduate school: Shanghai Health School.
Masterpiece: Chinese medicine treats aplastic anemia and acute jaundice (serum hepatitis).
Personal profile
Engaged in clinical, teaching and scientific research of traditional Chinese medicine for more than 60 years. He is good at hematological diseases, liver diseases, heart diseases, senile diseases and incurable diseases, and especially has rich experience and unique opinions on hematological diseases, liver diseases and heart diseases. In addition to daily diagnosis and treatment, he is also responsible for the medical care of Gao Qian officials and the treatment of foreign guests. He has taught in lectures such as Synopsis of the Golden Chamber sponsored by the Chinese Medical Association, and the University of Tuberculosis Continuing Education sponsored by the Shanghai Tuberculosis Prevention and Control Center has taught the course of treating tuberculosis with Chinese medicine. Shanghai Municipal Health Bureau entrusts the1~ 5th session of TCM research class sponsored by Shanghai TCM Literature Museum as a teacher and the first academic inheritance tutor of famous and old TCM experts in China.
Honor achievement
He has published more than 40 papers, such as Treatment of Aplastic Anemia with Traditional Chinese Medicine, Acute Jaundice (Serum Hepatitis) and Syndrome Differentiation Treatment of Coronary Heart Disease. Co-authored more than ten books such as Prevention and Treatment of Tuberculosis, Clinical Essentials of Contemporary Famous Doctors (Blood Stasis), Coronary Heart Disease, Strange Diseases and Infertility. ), and the new theory of liver disease prevention and treatment. 1985 was commended by Shanghai Municipal Health Bureau as "fifty years' work in traditional Chinese medicine and contribution to medical development"; 1989 was selected as the biography of contemporary famous doctors in Shanghai; 1994 was included in Who's Who in the Contemporary World (China Volume); 1995 was selected into the Dictionary of Contemporary Advanced Professional and Technical Talents; And in 1995, he was named "famous old Chinese medicine practitioner in Shanghai".
achievements in scientific research
Acute critical aplastic anemia 1 case was cured by cooling blood, stopping bleeding and treating symptoms, warming kidney and strengthening spleen. The treatment of precocious puberty in young girls begins with masturbation to reduce fire in liver and kidney boys. In February,1997,65438 participated in the "Huatuo Cup" essay contest for the second time and won the special prize.
Nourishing yin and strengthening the body resistance, widening the chest and eliminating dampness, treating fatigue, and drinking 1998 won the gold medal in the international paper contest "Huatuo Cup, a new medicine for new medicine"
Academic viewpoint
First, pay attention to medical ethics.
Although medical skills are excellent, it is impossible to serve the people wholeheartedly without medical ethics. Although medical ethics are high, it is impossible to cure all intractable diseases without medical skills. Therefore, as a health worker, it is indispensable to attack morality with medical skills. This argument is not only the first lesson for every descendant, but also his "motto" for demanding and comparing himself.
Second, pay attention to spleen and kidney.
Kidney is congenital, spleen is acquired, and tonifying kidney should be the first step to strengthen the spleen. Qi is handsome blood, and blood is the mother of qi, so invigorating qi should precede benefiting blood.
Spleen and kidney theory
Kidney essence belongs to yin, kidney qi belongs to yang, kidney yin is also called true yin, kidney yang is also called true yang, kidney yang is sufficient, kidney yin is insufficient. Moreover, the yin and yang of the kidney not only restrict and depend on each other in the human body, but also maintain a relative dynamic balance. Therefore, kidney essence is the biochemical activity of bone marrow, and kidney essence deficiency is the biochemical deficiency of bone marrow.
Li Zhongyu said: "When the grain enters the stomach, Chen overflows into the six zang-organs, the qi comes out, and when it is in harmony with the five zang-organs, the blood comes out, while human resources think that the living are also." Explain that digestion of spleen and stomach makes blood angry. The five internal organs generate the cloud "kidney and bone are combined" and "it governs the spleen". That is to say, the relationship between spleen and kidney is the same as that of "kidney governs bone" and "blood is born in bone marrow" in modern medicine, indicating that spleen and kidney are the main organs of qi and blood.
Essence and blood alternate, essence and blood are full and essence and qi are poor, so the rise and fall of spleen and kidney in anemia patients is the main key.
2. On Qi and Blood
Qi plays a very important role in the human body. "The yin and yang of the five internal organs rise and fall unless the qi does not rise." Song said: "people are dominated by qi, and the ups and downs of yin and yang are also qi." The reason why blood is popular is qi. The reason why roewe yunhua is also qi, and the reason why the five zang-organs trust each other is also qi. From what Yang said, people realize that qi plays a very important role in the human body.
From the clinical treatment, we can see that the relationship between invigorating qi and enriching blood is Danggui Buxue Decoction, which is a common prescription for enriching blood due to internal deficiency, but the blood-enriching effect of Astragalus membranaceus in this prescription is five times greater than that of Danggui. Why? This is the saying that "yang is associated with yin" and "blood loss is beneficial to qi", that is, "tangible blood is born from intangible qi". From the perspective of qi dynamics, the products of transforming qi have made great contributions to the power of removing blood stasis. For example, if the prescription for promoting blood circulation and removing blood stasis is added with the agent for promoting qi circulation and soothing the liver, the effect of removing blood stasis will be stronger. For example, in addition to Taohong Siwu Decoction, Xuefu Zhuyu Decoction also has Sinisan for soothing the liver and regulating qi. Clinically, this prescription is quite effective in treating headache, chest pain, impassability of menstruation, and purple lips caused by blood stasis. It shows that the products of promoting blood circulation and regulating qi are very helpful for removing blood stasis.
3. "Aplastic anemia", mainly deficiency, is mainly related to spleen and kidney (especially kidney). We divide it into "yang deficiency, yin deficiency and yin and yang deficiency", sometimes accompanied by blood stasis or blood heat. In treatment, regulating yin and yang and nourishing qi and blood are the main methods to treat this disease. If there are complications, it is necessary to treat both the symptoms and root causes, so as to remove blood stasis and promote blood circulation, clear heat and cool blood (regulating yin and yang mainly refers to spleen and kidney, especially kidney yin and kidney yang).
"Leukemia" is mostly empirical in appearance, but in fact it is virtual in essence and real in essence, especially in the later stage. Its symptoms are very complicated, generally divided into epidemic febrile disease type, blood heat type, blood stasis type, liver depression type, yin deficiency type, yang deficiency type, yin and yang deficiency type and so on. In treatment, we should adopt the method of syndrome differentiation according to the complexity of symptoms, or treat symptoms and signs first, or treat both the symptoms and the root causes.
4. Dampness is blood stasis, blood stasis is dampness stagnation, diuresis has the power of removing blood stasis, and blood circulation has the power of infiltrating dampness.
Six evils (wind, cold, heat, dampness, dryness and fire) can influence each other and transform each other. Especially when a person is not healthy, he will take advantage of it, and dampness is one of the six evils. It can not only cause harm alone, but also combine with other evils. The function of transporting water and dampness in human body mainly lies in spleen (including kidney and lung), so deficiency of spleen-yang will cause "dampness trapping spleen" and cause disease. Severe hepatitis is more common in clinic, mainly due to dampness and blood stasis, so it is often used to promote blood circulation and ooze dampness. There is a certain difference between diuresis and promoting blood circulation. For those whose dampness is heavier than blood stasis, diuresis is the main method, and for those with obvious blood stasis, blood stasis is the main method. However, those who are not obvious in dampness and blood stasis should also be given blood-activating drugs, and those who are not obvious in blood stasis should also be given Jiali wet agent. This is called "promoting diuresis has the function of removing blood stasis, and promoting blood circulation has the function of infiltrating dampness." Pathologically speaking, all those who accumulate dampness will cause blood stasis, and those who accumulate blood stasis will also cause dampness, so we must take care of both sides in treatment.
Medication characteristics
Promote gallbladder and remove blood stasis, skillfully use rhubarb; Supplementing qi and nourishing yin, using two ginseng skillfully. Yan Moumou, male, 3 1 year old. First visit1988 March 3 1. Chief complaint: jaundice lasted for ten weeks.
Self-reported liver pain, moderate appetite, cold appetite, but after eating, I feel abdominal distension, bitter taste, poor sleep, itchy skin and poor sweating. The stool is small and unpleasant, thin and yellow, with oily surface and dark yellow urine.
Diagnosis; Depression, bitter face, dark yellow eyes, yellow purple and dry skin. Pressing the second finger under the rib of the liver will hurt, but not under the rib of the spleen. There is no difference in heart and lung, rough tongue coating and the number of pulse strings.
Syndrome differentiation: damp-heat in liver and gallbladder, blood stasis.
Treatment: clearing liver and gallbladder, detoxifying and removing blood stasis.
Prescription: Herba Artemisiae Scopariae 15g, Radix et Rhizoma Rhei (below) 5, Fructus Gardeniae preparata 6g, Radix Gentianae 15g, Radix Angelicae Sinensis 15g, Caulis Sargentodoxae 20g, Herba Patriniae 30g, Radix Glycyrrhizae 6g, Radix Bupleuri 5g, Radix Paeoniae Rubra 9g each, and Fructus Aurantii Immaturus 5g.
Secondary diagnosis: April 7: After taking the medicine, abdominal distension was relieved, pain in the liver area improved, the skin was still itchy, the tongue coating was thick and greasy, and the pulse was thin.
Prescription: Sichuan rhubarb is increased to 8g, Camptotheca acuminata is increased to 18g, and then14g is taken.
Third consultation: April 23rd. Liver function reexamination showed that total bilirubin 1 1mg%, 1 min bilirubin 3mg%. Alanine transaminase and turbidity test were normal, but liver swelling and pain and skin itching were not obvious. Thin and greasy tongue coating, thin pulse. If the effect is achieved in advance, the treatment of supplementing qi and nourishing yin should be carried out according to law.
Prescription: Herba Artemisiae Scopariae 15g, Radix et Rhizoma Rhei (bottom) 9g, Fructus Gardeniae (each) 6g, Radix Bupleuri 5g, Radix Paeoniae Rubra (each) 15g, Radix Rehmanniae 12g, Fructus Aurantii Immaturus 5g, Radix Glycyrrhizae 6g, Semen Militaris 30g, Radix Gentianae 15g, Radix Gentianae. 2g of sun-dried ginseng, 2g of American ginseng, and another decoction to make tea twice a day.
After taking 7 doses, the total bilirubin was 6.2mg%, and bilirubin per minute was 2. 1 mg%, and then taking 7 doses. After taking the medicine, jaundice gradually subsided, sleep improved, liver ribs just arrived, skin itching disappeared, and defecation was also adjusted. The total bilirubin decreased to 5.7mg% after reexamination, and decreased to 1 .2 mg% after1min. Ask to be discharged for treatment. During outpatient follow-up after discharge, three methods were used to increase the loss, of which Sichuan rhubarb was used to12g; ; On July 2 1 re-examination, all jaundice subsided and all liver functions were normal. After half a year, I will resume full-time work.
Note: Cholestasis hepatitis is an acute intrahepatic cholestasis hepatitis with symptoms similar to acute icteric hepatitis. After three treatments, although alanine aminotransferase was normal, bilirubin gradually increased, reaching a maximum of more than 33.2mg%. The main problems to be solved in consultation are: (1) persistent jaundice; (2) The total bilirubin in laboratory examination is obviously higher. It is manifested as damp-heat in the liver and gallbladder, such as jaundice, large and painful liver, bitter mouth and dry mouth, aversion to cold, abdominal distension, itchy and dry skin; The stool is uncomfortable, the amount is small and thin, the color is yellow, and the surface is like oil; Urine is dark yellow; Rough tongue coating, number of pulse strings and so on. Its pathogenesis is damp-heat pulse, stagnation of liver and gallbladder, stagnation of liver qi, abnormal bile, oozing blood and overflowing skin. Therefore, Longdan Xiegan Decoction combined with Yinchenhao Decoction is used to soothe the liver, benefit the gallbladder, clear away heat and promote diuresis, and cool the blood and turn yellow. The patient has loose stools today, whether it can be used. In fact, rhubarb has the functions of attacking depression and removing blood stasis, cooling blood, benefiting gallbladder and relieving jaundice, purging fire and detoxifying, and is suitable for cases with severe damp heat. In actual treatment, rhubarb mainly removes blood stasis, cools blood, promotes gallbladder function and clears fu organs, and the dosage is gradually increasing. When using raw rhubarb, we must pay attention to the characteristics of poor defecation, less yellow color and oily face, plus abdominal distension, rough tongue coating, rapid pulse, damp heat blocking the intestine and poor viscera, but it is no harm to use rhubarb. Not only does it not have the disadvantages of diarrhea, but it makes the stool from difficult to refreshing, from thin to shaped, and other clinical symptoms gradually disappear. Laboratory examination 1 minute total bilirubin and bilirubin gradually decreased, which is not the result of blindly rhubarb, but its importance is obvious. At the same time, rhubarb has two other functions: first, it is compatible with Radix Paeoniae Rubra and Radix Angelicae Sinensis to promote blood circulation and remove blood stasis; Secondly, cooperate with Camptotheca acuminata to cool blood, dispel wind and relieve itching. Using this medicine can not only benefit gallbladder and relieve jaundice, but also remove blood stasis and promote blood circulation to improve liver depression. In short, blindly using rhubarb is beneficial to the functions of dredging the bowels, removing blood stasis and promoting blood circulation, cooling blood and relieving itching. It is really wonderful to make the finishing point in the prescription.
Sun-dried ginseng and American ginseng use soup instead of tea, which has a strong function of benefiting qi and nourishing yin. The dosage ratio of them depends on the needs of the disease. Dry mouth, upset, poor sleep, and abnormal fatigue are all due to deficiency of both qi and yin, so it is necessary to strengthen the body and tonify the deficiency, and urgently use raw ginseng and American ginseng to replenish qi and nourish yin together to strengthen the body. Improve your immunity and disease resistance.
Medical theory
Qiao Yang's Experience in Treating Hematological Diseases
1. Aplastic anemia "Aplastic anemia" is a blood system disease characterized by pancytopenia due to low hematopoietic function. According to its symptoms and signs, it can be seen in blood syndrome and physical weakness. Seeing blood deficiency at the initial diagnosis, paying attention to the treatment of blood deficiency, from the first day, conditioning spleen and kidney, assisting blood circulation and removing blood stasis. Drugs for promoting blood circulation and removing blood stasis can improve blood circulation, which is beneficial to the development, proliferation, differentiation and mature release of bone marrow hematopoietic cells. If qi deficiency and blood circulation are slow, it will also cause blood stasis. Patients with aplastic anemia should use the method of promoting blood circulation and removing blood stasis with caution when stopping bleeding and bleeding too much. On the one hand, menstrual blood is precipitated after bleeding, and removing blood stasis can promote regeneration. On the other hand, after the bleeding stops, "aplastic anemia" is often treated with drugs that warm the spleen and kidney. Drugs that promote blood circulation and remove blood stasis improve microcirculation by dilating microvessels, which is beneficial to bone marrow and promotes hematopoiesis.
Second, chronic myeloid leukemia
Leukemia is a malignant proliferative disease of hematopoietic tissue, and its condition is dangerous, such as fever, hemorrhage, anemia, lymphadenopathy of liver and spleen, etc. , commonly known as "hematological cancer". According to the principle of combining syndrome differentiation and treatment with disease differentiation, leukemia belongs to the category of blood syndrome, strain and disease accumulation. Acute leukemia or chronic leukemia, which belongs to the category of epidemic febrile diseases, shall be treated as epidemic febrile diseases. Clinical deficiency and excess are mutually seen. Leukemia is an "evil thing", and the treatment mainly focuses on attacking evil, clearing away heat and toxic materials, promoting blood circulation and removing blood stasis to break its spirit. Rhinoceros horn (instead of buffalo horn) can cool and disperse blood and reduce white blood cells. Patients with blood syndrome often choose Hedyotis diffusa, Scutellaria barbata, Prunella vulgaris, Malangen, Belamcanda and other traditional Chinese medicines with detoxification and anticancer effects. Leukemia is also a commonly used medicine.
Qiao Yangxian's experience in treating blood syndrome.
Source: Shaanxi Traditional Chinese Medicine1986; 7 (1): 447 Abstract: 1. Most new diseases are caused by fire, and the internal heat is strong, which goes against the blood. The disease is located in blood, and the cause is often qi. However, the distinction between qi deficiency and qi deficiency is related to fire. Too hot is fire, too much is fire. If it is hot, it is true qi, but in fact, qi will go against the chaos and force blood to rush. The main treatment is clearing away heat and purging fire, supplemented by drugs for lowering qi or reducing adverse qi. Upper bleeding is mostly treated with drugs that reduce the adverse flow, which means "the blood flows smoothly." For example, excessive liver-fire, liver-qi upwelling and blood transportation leading to vomiting blood and epistaxis, please choose Gentiana macrophylla, Scutellaria baicalensis Georgi, Cortex Moutan, Radix Rehmanniae, etc. For example, Yangming vomited blood due to the rising of qi and fire, and Xiexin decoction was often used as the main prescription to reduce stomach and guide blood. Scutellaria baicalensis Georgi, Fructus Gardeniae, Semen Plantaginis, etc. Commonly used for clearing away lung-heat, such as Bulbus Allii Macrostemon Powder, which causes blood cough and bleeding due to heat injury to lung collaterals and excessive qi. In the examination of fire infection, rhubarb is used to clean up the real fire, so that it can draw blood downward, promote blood circulation, cool blood and stop bleeding.
Second, chronic illness is mostly due to deficiency of heat and qi. Bleeding for a long time is easy to expel heat, and bleeding will reduce heat. Therefore, blood heat erupts, heat lasts for a long time with blood, and qi loss with blood. Deficiency of both qi and yang is more common in clinic, or heat image is less. Medication tends to be warm, and qi should be regulated to treat blood. First, blood and qi should be supplemented, qi should suck blood, and spleen should control blood. The method of warming middle warmer, invigorating spleen and qi, nourishing the source of blood production is the key to the method of enriching blood for blood syndrome, and it is also an effective method for blood syndrome of heat deficiency and qi deficiency.
Third, blood syndrome is more common in patients with dampness and blood stasis. In addition to bleeding, it is often accompanied by phlegm and dampness. Dampness stagnation is easy to cause blood stasis, and blood stasis is easy to produce dampness. Promoting blood circulation and promoting diuresis, promoting diuresis and removing blood stasis. As long as there is the connotation of dampness and turbidity, it is possible to treat both stasis and dampness. When taking medicine, he thinks that astringent drugs should not be used suddenly when blood syndrome is wet, and greasy tonics should not be used purely when blood is too long. On the contrary, in the products of eliminating dampness, promoting blood circulation and stopping bleeding, drugs that benefit qi and nourish yin but are not greasy are often used.
Fourth, the early prevention of massive hemorrhage is to point out that there is too much blood, or heat enters the blood, or blood stasis is deep. Early prevention can greatly reduce the mortality of patients with massive hemorrhage. The so-called "early" means: first, early detection of symptoms of acute syndrome, advocating that patients with blood loss have slow pulse and good prognosis. If the pulse is tight, impatient or strong, it is ominous, and attention should be paid to prevent bleeding again. Second, early truncation, control bleeding, or prevent further aggravation of bleeding. If acute leukemia is accompanied by massive hemorrhage, the fire is toxic and pathogenic, and the clinical manifestations are like fever, it is advisable to attack the excess and supplement the deficiency. In the empirical study, it is necessary to purge the fire, draw the salary from the bottom of the pot, and nourish the blood when the fire disappears, so it is advisable to use a large dose of cold products as early as possible. Take the power of clearing away heat and toxic materials and cleaning up real fire. As long as you see that heat toxin is seriously accompanied by irritability, or your mental state is slightly abnormal, it can be used in clearing away the camp, cooling blood, promoting blood circulation and detoxifying to prevent syndrome accumulation.