Product introduction of omeprazole enteric-coated tablets
Generic name: omeprazole enteric-coated tablets
Manufacturer: Zhejiang Huali Nanhu Pharmaceutical Co., Ltd.
Approval number: National Medicine Zhunzi H 19990 160
Drug specification: 20mg* 15 tablets.
Drug price: ￥ 17. 1 yuan.
Instructions for omeprazole enteric-coated tablets
Omeprazole enteric-coated tablets
Product Name Omeprazole Enteric-coated Tablets (Tegel)
Omeprazole enteric-coated tablets
Full Pinyin Omela Zuo Changrong Film (tegel)
The main ingredient is omeprazole.
Chemical name: 5- methoxy -2-{[(4- methoxy-3,5-dimethyl -2- pyridyl)-methyl]-sulfoxide }- 1H- benzimidazole.
Molecular formula: C 17H 19N3O3S.
Molecular weight: 345.4 1
Characteristics Omeprazole enteric-coated tablets (Tegel) are enteric-coated tablets, which are white or white-like after coating is removed.
Indications/Functions: It is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis, Zhuo-Ai syndrome (gastrinoma).
Specification model 20mg* 15s
Usage and dosage: Take orally, but don't chew. 1. Peptic ulcer: 20mg once (1 tablet once), 1 ~ twice a day. Swallow it every morning or once in the morning and evening, and the course of treatment for gastric ulcer is generally 4-8 weeks. The course of treatment of duodenal ulcer is usually 2 ~ 4 weeks; 2. Reflux esophagitis: 20 ~ 60 mg once (1 ~ 3 tablets once), 1 ~ 2 times a day. Swallow it in the morning or once in the morning and evening, and the course of treatment is usually 4 ~ 8 weeks; 3. Zhuo-Ai syndrome: 60mg once (3 tablets once), once a day 1 time. In the future, the total daily dose can be adjusted to 20 ~ 120 mg (1 ~ 6 tablets) according to the condition. If the total daily dose needs to exceed 80mg(4 tablets), it should be taken twice.
Adverse reactions Omeprazole enteric-coated capsules are well tolerated, and the common adverse reactions are diarrhea, headache and nausea. Abdominal pain, flatulence and constipation. Occasionally, serum transaminase (ALT, AST) increased. Rash, dizziness, lethargy, insomnia, etc. These adverse reactions are usually mild and can disappear automatically, regardless of dosage. No serious adverse reactions were found after long-term treatment, but gastric epithelial cell proliferation and atrophic gastritis may occur in some cases.
Contraindications: allergic to omeprazole enteric-coated tablets (Tiger), severely renal insufficiency and infants are prohibited.
Precautions 1. In the treatment of gastric ulcer, the possibility of gastric ulcer should be ruled out first, because the treatment with omeprazole enteric-coated tablets (Tegel) can alleviate its symptoms, thus delaying treatment. 2. Patients with hepatic and renal insufficiency should use it with caution. 3. Omeprazole enteric-coated tablets (Tegel) are enteric-coated capsules, so be careful not to chew them when taking them, so as to avoid the premature release of drugs in the stomach and affect the curative effect.
Children's medication is unclear.
Omeprazole enteric-coated tablets (tegel) for elderly patients have not been used in this experiment, and there are no reliable references.
Drug treatment for pregnant and lactating women is not clear.
Drug interaction omeprazole enteric-coated tablets (tegel) can delay the elimination of drugs metabolized by the liver in vivo, such as diazepam, phenytoin sodium, warfarin and nifedipine. When omeprazole enteric-coated tablets (TAG) are combined with the above drugs, the dosage of the latter should be reduced.
The drug overdose is not clear.
Pharmacology and toxicology proton pump inhibitors. Omeprazole enteric-coated tablets (Tiger) are fat-soluble weakly alkaline drugs. It is easy to concentrate in acidic environment, so it can be specifically distributed in the secretory tubules of parietal cells of gastric mucosa after oral administration, and it will be converted into the active form of sulfenamide in this high-acid environment, and then irreversibly combine with the sulfhydryl groups of H+ and K+-ATPase (also known as proton pump) in parietal cell secretory membrane through disulfide bonds to form a complex of sulfenamide and proton pump, thus inhibiting the activity of this enzyme and blocking the next gastric acid secretion. Therefore, omeprazole enteric-coated tablets (TAG) have a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.
Pharmacokinetics is unclear.
Store in a cool and dry place and keep it sealed.
Packaging plastic bottles, 20mg/s, 15s/ bottle.
Valid for 24 months.
The approval number is H 19990 160.
Zhejiang huali Nanhu pharmaceutical co., ltd.
Efficacy and Function of Omeprazole Enteric-coated Tablets (Tegel) Omeprazole Enteric-coated Tablets (Tegel) are suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zooeai syndrome (gastrinoma).
Common problems in taking omeprazole enteric-coated tablets
Q: What are the adverse reactions of omeprazole enteric-coated tablets (Tiger)?
A: Omeprazole enteric-coated capsules are well tolerated, and the common adverse reactions are diarrhea, headache and nausea. Abdominal pain, flatulence and constipation. Occasionally, serum transaminase (ALT, AST) increased. Rash, dizziness, lethargy, insomnia, etc. These adverse reactions are usually mild and can disappear automatically, regardless of dosage. No serious adverse reactions were found after long-term treatment, but gastric epithelial cell proliferation and atrophic gastritis may occur in some cases.