Current location - Education and Training Encyclopedia - Graduation thesis - A paper on AIDS
A paper on AIDS
Published a research paper entitled "Long-term reconstruction of adult hematopoietic stem cells edited by CRISPR gene in patients with AIDS complicated with acute lymphoblastic leukemia", published in the New England Journal of Medicine. Deng Hongkui from Peking University-Tsinghua University Joint Center for Life Sciences, Chen Hu from the Fifth Medical Center of PLA General Hospital and Wu Hao from Beijing You 'an Hospital affiliated to Capital Medical University jointly pointed out.

This sign? The world's first case of treating AIDS and leukemia patients by gene editing stem cell transplantation was completed by scientists in China. The results show that using CRISPR/Cas9 technology, scientists can edit human hematopoietic stem cells, and the stem cells after gene editing can stably rebuild the hematopoietic system in animal models for a long time, and the peripheral blood cells produced by them have the ability to resist AIDS and leukemia.

The effect of gene editing is always stable in blood cells, and no side effects such as off-target caused by gene editing are found. The feasibility and safety of gene editing hematopoietic stem cells in clinical application will certainly promote and promote the clinical application of this technology. Because it has not been officially used in clinic at present, everyone is looking forward to better development in this field, thus benefiting mankind and the world.

Since experts can study and do relevant papers, the feasibility is still relatively large. But as a layman, there is no way to judge, but this is a good thing, so I hope it can be better promoted. Ensure that the achievements of modern civilization are applied to patients as soon as possible, so that patients can completely get rid of the entanglement of diseases.