1. agarwal s, Loh YH, McLoughlin EM, Huang j, park IH, miller JD, huo h, okuka m, Dos Reis RM, Loewer S, Ng HH, kiefer DL, Goldman FD, klinger hutz AJ, Liu l, Daley GQ. Telomere elongation of pluripotent stem cells induced by patients with congenital keratosis. Nature 464:292-296(20 10).

2. Huang J, okuka M, Wang F, Zuo B, Liang P, Calmbach K, Liu L, Keefe DL. Producing pluripotent stem cells from the eggs of aging mice. Aging Cells Online (2009).

3. The correlation between the expression and methylation of imprinted genes and the pluripotency of parthenogenetic embryonic stem cells. Human Molecular Genetics18: 2177-2187 (2009).

4. Liu Ning, Lu Min, Feng Xiaomei, Ma Fuxiang, Fang, Tian Xiaomei, Ren Qing, Zhang Lei, Liu Bo, Huang Peiping, Liu Lei and Han. Exogenous Nanog can alleviate but not reverse the differentiation of embryonic stem cells induced by PI3K signal inhibition. Journal of Cell Biochemistry106:1041-1047 (2009).

5. Chen Z, Liu Z, Huang J, Amano T, Li C, Cao S, Wu C, Liu B, Zhou L, Carter MG, Keefe DL, Yang X, Liu L. Parthenogenetic mice were directly produced from parthenogenetic embryonic stem cells. Stem cells 27: 2136-2145 (2009).

6. Telomeres and reproductive aging. Reproduction, fertility and development 21:10-14 (2009).

7. Cao, Wang, Chen, Liu, Mei, Wu, Huang, Li, Zhou and Liu. Isolation and culture of primary colonies of bovine embryonic stem cells. Laboratory animal science magazine series a. 3 1 1A:368-376 (2009)。

8. Research status and prospect of induced pluripotent stem cells. China life science. 52:622-636 (2009).

9. Huang J, Deng K, Wu H, Liu Z, Chen Z, Cao S, Zhou L, Ye X, Keefe DL, Liu L. Embryonic stem cells were injected into four-cell or eight-cell embryos by piezoelectric micromanipulation to effectively produce mice. Stem cell 26:1883-1890 (2008)

10. Liu L, S.M. Bailey, M. okuka, P. Mu? Oz, C. Li, L. Zhou, C. Wu, E. Czerwiec, L. Sandler, A. Seyfang, and Keefe. Telomere lengthening in early development. Nature Cell Biology 9:1436-1441(2007)

1 1. Germ stem cells and neooogenesis in adult ovaries. Developmental Biology 306:112-120 (2007)

12. Liu L and Keefe DL. Chapter 15 nuclear transplantation method for studying aging in molecular biology methods: biological aging: methods and protocols. Humana Press, Totova, New Jersey. In 2007

13. telomere and meiotic dysfunction related to female aging. Cell and Molecular Life Sciences 64: 139- 143 (2007)

14. Wang x, Liu l, Montagni c, reed t, Deng. Haploid deficiency of Parp 1 will accelerate centrosome amplification, telomere shortening, genetic instability, apoptosis and embryo death related to Brca 1. Cell Death & Differentiation 14:924-93 1 (2007)

15. Dai, Y, L. Wang, H. Wang, Y. Liu, Q. Lyu, N. Li, D. L. Keefe, D. F. albertini and L. Liu. Abnormal central body weight after somatic cell nuclear transfer (SCNT) of bovine oocytes. Reproduction131:1051-kloc-0/061(2006).

16.Liu, L., Franco, S., B., Moens, P.B., M.A. and Keefe, D.L. Irregular telomeres damage meiotic synapses and recombination in mice. Proceedings of the National Academy of Sciences101:6496-6501

17. Liu, Di Girolamo, Navarro, and Keefe. Telomerase deficiency impairs the differentiation of mesenchymal stem cells. Experimental Cell Research 294: 1-8 (2004)

18. Liu, Trimarchi, Navarro, and Keefe. Oxidative stress leads to arsenic-induced telomere wear, chromosome instability and apoptosis. Journal of Biochemistry 278: 31998–32004 (2003)

19. Liu, Master, Dr. Trimarchi and Dr. Keefe. Functional telomere plays an important role in fertilization and early development of mouse germ cells. Developmental Biology 249:74-84 (2002)

20. Liu, L, and D.L. Keefe. Requirements of functional telomeres on metaphase chromosome arrangement and meiotic spindle integrity. EMBO report

2 1. Liu, Li, Deng, Tian, Yang. Activation of mammalian oocytes: principle and practice. In: Introduction to Mammalian Reproduction. Editor: Daulat ·r·p· tulsi Yani, Kluwer Academic Press, Massachusetts, USA. pp-

22. Liu, J.R. Trimarchi, P.Smith and D.L. Keefe. Mitochondrial dysfunction leads to telomere wear and genomic instability. Aging cell

James TremMarch, peter smith and David Keefe. Haploid activation rather than parthenogenetic activation leads to an increase in the incidence of mouse embryo apoptosis. reproductive biology

24.Trimarchi, J.R., Liu, L., Smith, P.J. and Keefe, D.L. Apoptosis recruited dual-pore potassium channels for steady-state volume regulation. American journal of physiology

25. Liu, Catherine Hamar, peter smith, Nobuya Inoue, David Keefe. Mitochondrial regulation of calcium signal at the beginning of development. Cellular calcium

26.Dinnyés, A., Dai, Y., Barber, M., Liu, L., Xu, J., Zhou, P., and Yang, X. Development of cloned embryos of adult rabbit fibroblasts: effects of activation treatment and preparation of donor cells. reproductive biology

27. Cloning efficiency and differentiation. Natural Biotechnology 19:406 (200 1) (corresponding).

28.Liu, L., Oldenbourg, R., Trimarchi, J. R. and Keefe, D.L. Reliable and Non-invasive Techniques for Mammalian Oocyte Spindle Imaging and Inspiration. Natural Biotechnology Chen Lingyi, Liu Ling. Present situation and prospect of induced pluripotent stem cells. Science is in China.

Chen Lingyi, Liu Ling. Research status and prospect of induced pluripotent stem cells. China science series c.

The relationship between the expression and methylation of impression genes of Li, Chen, Liu, Huang, Zhang, Zhou and pluripotency of parthenogenetic embryonic stem cells. Human molecular genetics

Cao, Wang, Chen, Liu, Mei, Wu, Huang, Li, Zhou, Liu. Isolation and Culture of Primary Colonies of Bovine Embryonic Stem Cells. laboratory animal science Magazine Series A.

Chen Z, Liu Z, Huang J, Amano T, Li C, Cao S, Wu C, Liu B, Zhou L, Carter MG, Keefe DL, Yang X, Liu L*. Parthenogenetic mice were directly produced from parthenogenetic embryonic stem cells. stem cells

Liu. Telomeres and Reproductive Aging. Reproduction, fertility and development

1. agarwal s, Loh YH, McLoughlin EM, Huang j, park IH, miller JD, huo h, okuka m, Dos Reis RM, Loewer S, Ng HH, kiefer DL, Goldman FD, klinger hutz AJ, Liu l, Daley GQ. . Telomere elongation of pluripotent stem cells induced by patients with congenital keratosis. nature

Huang J, okuka M, Wang F, Zuo B, Liang P, Calmbach K, Liu L*, Keefe DL. Producing pluripotent stem cells from the eggs of aging mice ... aging cells-

Huang J, okuka M, McLean M, Keefe DL, Liu L. . Susceptibility of telomeres to oxidative damage and chromosome instability of mouse embryos induced by cigarette smoke in vitro. Free radical biology and biology. medical science

Richards T, Wang F, Liu L, Baltz JM. . Amino acid transporter substrate can be used as an organic osmotic regulator to save mouse embryo development from hyperosmotic state in the late stage of densification ... Reproductive Biology

The genome-wide gene expression profiles of Liu N, Enkeman SA, Liang P, Hersmus R, Zanazi C, Huang J, Wu C, Chen Z, Lu Eyenga LH, Keefe DL, Liu L ... reveal abnormal MAPK and Wnt signaling pathways related to early parthenogenesis ... J Mol cell biology.

Liu Ning, Min Lu, Feng Xiaomei, Ma Fuxiang, Fang, Tian Xiaomei, Ren Qing, Zhang Lin, Liu Bo, Huang Peiping, Liu Lin, Han ... J cell biochemistry

Liu, Hu, Zheng, Pan, X, Li, M, Togun, ta, Tuck, D, Pelizzola, M, Huang, J, Ye, X, Yin, Y, Liu, M, Li, C, Chen, Z, Wang, F, Zhou, L, Chen. Germline ability of parthenogenetic embryonic stem cells from adult mouse oocytes. human gene

Huang, Wang, Okubo, Liu, Ji, Ye, Zuo, Li, Liang Ping, Ge Weihua, Zebris, Liu Xiaolan, Liu .. Relationship between telomere length and embryonic stem cells/induced pluripotency .. Cell resolution.

Molecular Perspective of Heterogeneity of Telomere Reprogramming of Pluripotent Stem Cells Induced by Wang F, Yin Y, Ye X, Liu K, Zhu H, Wang L, Chi Ou Ya M, okuka M, Ji G, Dan J, Zuo B, Li M, Zhang Q, Liu N, Chen L, Pan X, Gagos S, Keefe DL and Liu L. Cell area