2 Overview exudative erythema multiforme, also known as erythema multiforme, is an acute inflammatory skin disease with unknown etiology. Exudative erythema multiforme belongs to connective tissue disease, which is characterized by the damage of skin and mucosa diversity.
Symptoms are acute, including high fever, general malaise, headache, sore throat, dysphagia, abdominal pain, diarrhea and joint pain, which quickly turn into a critical state of general failure. On the day of fever or a few days later, a polymorphic rash appears, which varies in size, sparse or fused, and spreads rapidly around. There are large or small blisters and bullae in the center, which can spread to the whole body skin within one day, but the scalp is rare. Congestion, erosion, exudation and bleeding at the junction of buccal mucosa, tongue, gums and oral mucosa and skin lead to difficulty in eating and swallowing. There are purulent secretions in the conjunctiva of both eyes, and blisters and erosion may occur at the junction of eyelid conjunctiva and skin. * * * The surrounding area is red, swollen, painful and festering. The course of the disease lasts for 2 ~ 3 weeks, and after 3 ~ 6 weeks, the rash gradually disappears, leaving peeling and pigmentation. The course of disease is often accompanied by joint pain, angina pectoris, bronchitis and bronchopneumonia. Peripheral blood leukocytes increase, erythrocyte sedimentation rate often rises rapidly, and C-reactive protein can be positive.
4. Diagnosis 4. 1 chilblain is more common in winter and exposed parts of the skin, and mucosa is not common. Itching, especially in the case of high temperature, local edema and infiltration and venous congestion.
4.2 Herpes-like dermatitis is a polymorphic rash, but most of them are arranged in a ring or semi-ring. Chronic course of disease, easy to relapse. It itches badly. See more torso and limbs. Eosinophils in blood and blisters increased significantly and potassium iodide test was positive. Histopathology showed that there were tension blisters under the epidermis, which contained neutrophils and eosinophils.
4.3 Urticaria rash has no fixed place, with rapid onset and regression. The rash is a single wheal, generally without blisters, and it is itchy.
4.4 Drug eruption has a history of taking drugs, and it can be cured after stopping taking drugs, which has nothing to do with seasons and has no certain prone parts.
5 How to treat it