People will decompose and digest after eating various foods, so even if they eat collagen, the collagen synthesized after decomposition is very different from the collagen they want to form. Collagen will have many dipeptides and tripeptides directly absorbed into the blood, which also has clear scientific evidence. In 2005, Japanese scholars published papers to study the absorption of hydrolyzed collagen. They found that hydroxyproline could hardly be detected in human plasma before eating hydrolyzed collagen. After eating 1 to 2 hours, the content of hydroxyproline in blood increased greatly. Among them, hydroxyproline accounts for about 25%.
Acids exist in dipeptide tripeptide. There are peptidases in human plasma, which can break down peptides entering the blood into amino acids. Other peptides can usually be decomposed by half in just a few minutes, and they come from the "proline-hydroxyproline" of collagen.
Amino acid dipeptide, after 24 hours, 75% is still left. This kind of dipeptide accounts for the vast majority of collagen dipeptides in blood.
Will so many stable dipeptides help the skin synthesize collagen? Businessmen just use this "problem" as a "fact" to fool. Actually,
Human protein should be synthesized in cells, but these dipeptides and tripeptides cannot enter cells as raw materials for protein synthesis. In other words, they are absorbed into the blood, but they can't be used, and finally they are excreted.
Outside.
In some cell experiments, scientists found that these dipeptides can be used as "signals" to promote the aggregation and growth of fibroblasts. Based on this, some people speculate that they may have the effect of promoting wound healing. Because the joints are soft
Bone is also composed of collagen, and some scientists speculate whether collagen supplementation can help maintain joint health and relieve joint discomfort. The promoters of collagen, on the other hand, directly borrowed this concept, claiming that these absorption.
Although peptide can not directly participate, it can be used as a signal to promote the synthesis of skin collagen. There is no scientific evidence to support this view. 20 1 1 In March, Kalida, a giant in the world collagen industry, summarized the research on this effect in scientific literature and applied to the European Food Safety Agency (EFSA) for approval of "hydrolyzed collagen".
Keep your joints healthy. " After two supplementary materials, the EFSA Scientific Committee reached a clear conclusion in June: these studies cannot support this conclusion.
In short, whether it is the literature summary of Kalida or other "latest formulas", taking oral collagen for beauty and skin care is just an imagination. After so many years of research in this field, there is still no convincing evidence. As a consumer, the wisest judgment is that this function does not exist!