1856, in order to explore the law of controlling hybrid formation and development, Mendel conducted a pea hybridization experiment in Augustine Monastery in Bruen (now Czech Republic) for 8 years. In his experiments, he has very clear ideas about what problems to solve, what materials to choose and how to analyze the results. He created a whole new set of genetic research methods, mainly including: single factor analysis, mathematical statistics and cross-test experiments. The rigorous and correct scientific method makes Mendel's experimental results truly reflect the nature of biological inheritance.
1865, Mendel reported and explained the purpose, method and process of his pea hybridization experiment twice (February 8 and March 8) at the monthly meeting of the Natural Science Association in Bloom, Austria. In this report, Mendel conducted in-depth theoretical argumentation based on statistical experimental data; His unique genetic analysis method is expounded in detail. A new concept of separation and combination of genetic factors is put forward.
1866, Mendel's pea hybridization experiment results were published in the fourth volume of Journal of Bloom Natural Science Association with a paper entitled "Plant Hybridization Experiment" after reviewing the experimental records in various years, and no mistakes were found. In this paper of about 30 thousand words, Mendel faithfully described his great discovery; Two genetic laws are summarized, which are called "separation law" and "free combination law".
Mendel's papers have been distributed to the libraries of German Botanical Society, Royal Society, French Academy of Sciences, Vienna University in Austria, Columbia University in the United States and other domestic and foreign 138 scientific research institutions and universities. But there was no response from all sides, and the whole scientific community remained silent about it. No one realized that there was an epoch-making discovery in Mendel's paper.
In this way, Mendel's thesis, regarded by later generations as an important model of scientific experiments and rich and thorough information, surpassed the academic level at that time because of its "premature time" and fell asleep in obscurity on dusty library shelves in various countries for more than 30 years.
1 July, 899 to1June, 2000 to1June, 2000, in the name of "International Plant Hybridization Conference", at the1International Genetics Conference held in London, England, British geneticist batson (W. batson, 186 1 ~ 1926) read the article "hybridization and hybrid breeding as a scientific research method", reminding people to pay for it. As early as 1897, batson began to conduct hybrid experiments on the crown shape and feather color of domestic chickens. In the experiment, he not only found the separation ratio similar to Mendel's, but also understood the importance of statistical analysis of hybrid offspring. It can be seen that batson is very close to Mendel more than 30 years ago, both in research methods and experimental results. This also shows that the time is ripe for Mendel's genetic theory to be accepted by academic circles.
In the second year after the meeting, three papers were published in the volume 18 of the German Botanical Society in Berlin, namely, separation phenomenon, a hybrid of Defrees, Mendel's law of interspecific hybrid offspring of Collens and artificial pea hybridization of Qiu Schoemaker (these three papers were received on165438, March 900, respectively). In this way, on the eve of the publication of their research papers, three botanists from different countries discovered Mendel's paper "Plant Hybridization Experiment" as early as 1866 almost at the same time through their independent plant hybridization experiments and consulting related literature. In the history of science, this great event is called the rediscovery of Mendel's law.
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Hemingway, the author of The Old Man and the Sea, only one-eighth of his creative pursuit is expressed in words, and the remaining seven-eigh