In the reform, the center actively changed its concept, broke through the shackles of the old model of health and epidemic prevention, actively explored new ways of disease prevention and control, made clear the organization's goal orientation and function orientation, actively shifted its focus of work, and continuously improved the level of public health services. It has successively won the titles of National Advanced Collective for Planned Immunization, Tuberculosis Prevention and Treatment, Occupational Disease Prevention and Treatment, Chronic Disease Prevention and Treatment, Provincial Party Committee and Provincial Government Advanced Collective for Fighting SARS, and Provincial and Municipal Civilized Units.
Adhering to the road of "developing defense through science and education", since 1999, the center has undertaken 38 scientific research projects at or above the municipal level, won provincial and municipal scientific and technological progress awards 19, and published 303 professional academic papers, including national 166. In 2000, it was confirmed for the first time in China that a DNA fragment related to bacterial virulence carried in the genome of Escherichia coli was the cause of unexplained diarrhea in infants, and a new subtype of ε-compactin was discovered for the first time. In 2002, the research achievement of "quickly eliminating organophosphorus pesticide residues in vegetables" was transformed into a product "pure vegetable treasure" after applying for a national invention patent, which was well received by the society and effectively prevented and controlled food poisoning caused by organophosphorus pesticide residues in vegetables. On April 24, 2003, the gene fragment of SARS virus was detected in the throat swab of patients, which was an earlier unit in China at that time. In May, 2003, he presided over the research and development of "negative pressure cover for moving bed unit for SARS prevention and control" and won the national invention patent. From June 5438 to October 2005 10, the first case of human-to-human transmission of brucellosis was found in China. From June 5438 to February 2005, seagull-shaped bacteria were isolated from patients with community-acquired gastroenteritis for the first time in China.