Lu, born in Guangxi, 1964, received his doctorate from Sun Yat-sen University in 2005. At present, he is a professor at the College of Pharmaceutical Sciences of Guangdong Pharmaceutical University, the head of the Department of Basic Chemistry, and the tutor of master students majoring in pharmaceutical chemistry. Engaged in the research of metal drugs, mainly for the synthesis and anti-tumor activity of small molecular metal vanadium compounds, the screening of transition metal drugs and so on. More than 60 papers have been published, among which many SCI papers have been published in foreign journals such as J.Inorg.Biochem, DNA and CELBIOL, J. COORD, etc. Chemistry, BIOL. INORG。 Chemistry.
Chinese name: Lu
Mbth: Jiazheng Road
Nationality: China.
Ethnic group: Zhuang nationality
Place of birth: Youjiang, Guangxi
Date of birth:1September, 964
Occupation: teacher
Graduates: Huazhong University of Science and Technology, Sun Yat-sen University.
Main achievements: Youjiang Medical College for Nationalities, third prize of scientific and technological achievements; The first prize of scientific and technological progress in Henan province
Masterpiece: bilingual textbook of inorganic chemistry
Research interests: medicinal chemistry and inorganic medicinal chemistry.
Work unit: Guangdong Pharmaceutical University.
Title: Professor
Basic information:
Lu, Ph.D., Professor, Head of the Department of Basic Chemistry, Guangdong Pharmaceutical University. 199 1 graduated from Huazhong university of science and technology (now Huazhong university of science and technology) and obtained
Master, research direction is bio-inorganic chemistry. 1993 10 Paper "Mechanism of Pingyangmycin Induced Cataract in Rats and Selenium Compounds"
The research on its influence won the excellent dissertation of Huazhong University of Science and Technology and the third prize. Guangxi Youjiang Medical College for Nationalities is from 199 1 to 200 1.
As a lecturer and associate professor, engaged in chemistry teaching and scientific research. From July 2000 to June 2006, 5438+0, University of Aberdeen (University
OfAberdeen) is a visiting scholar in the Department of Chemistry and participated in the project "Patellarine: Selective Copper (II) Complexing Agent".
Research. Graduated from Sun Yat-sen University in 2005 with a doctorate. His research direction is bio-inorganic chemistry. Since July 2005, in Guangdong pharmacy.
Hospital professor, postgraduate tutor of medicinal chemistry.
He has been engaged in the teaching and scientific research of inorganic medicinal chemistry and medicinal chemistry for many years. 20 10 was rated as an activist in the SCIentific and technological work of Guangdong pharmaceutical university, and published many sci research papers in recent years.
Education experience
65438+September 0982-65438+July 0986, the Department of Chemistry of Guangxi University for Nationalities received a bachelor's degree.
June 65438+July 0986-June 65438+August 0988, Department of Chemistry, Youjiang Teachers College for Nationalities, Guangxi, as a teaching assistant.
1988 September-1991June, Department of Chemistry, Huazhong University of Science and Technology (now Huazhong University of Science and Technology), obtained the Master of Science degree.
1991From July to August, 2002, he worked as a teaching assistant and lecturer in the Chemistry Department of Youjiang Medical College for Nationalities in Guangxi. 1997 65438+promoted to associate professor in February.
From July 2000 to June 2006, 5438+0, he was a visiting scholar at the Institute of Marine Natural Products, Department of Chemistry, Farbertin University, UK. I studied under Professor MarcelJaspars, and engaged in the research of copper-containing natural products with biological activity.
September 2002-June 2005, Sun Yat-sen University, School of Chemistry and Chemical Engineering, received a doctor of science degree.
Since July 2005, he has been a professor in the Department of Inorganic Chemistry, College of Pharmaceutical Sciences, Guangdong Pharmaceutical University, and is now the head of the Department of Basic Chemistry.
research direction
Inorganic medicinal chemistry, synthesis of small molecular antitumor drugs, screening and activity study of metal drugs
project
Major projects of new drugs of Ministry of Science and Technology, National Natural Science Foundation of China and Guangdong Natural Science Foundation of China.
Winning record
1, Study on the Mechanism of Cataract Induced by Reactive Oxygen Species, Henan Science and Technology Commission, First Prize of Henan Science and Technology Progress, 1992. 12 (seven people won the prize, ranking sixth).
2. ESR study on the mechanism of rat cataract induced by Pingyangmycin, Youjiang Medical College for Nationalities, second prize of scientific and technological achievements, 1993.438+00, the first winner.
3. Trace element analysis of leye county Twisted Blue Tea in Baise, Youjiang Medical College for Nationalities, third prize of scientific and technological achievements, 1999 38+02, the first winner.
academic writing
Jiazheng Road * (Lu), Hai Weiguo, Xiandongzheng,,, Jingjiang and Linquan.
Zang. Synthesis and characterization of asymmetric vanadium oxide complexes: DNA- binding, cleavage and biological activity. Journal of organic biochemistry, 20 12,
Xiang Wenliao, Jia Zhenglu *, Peng Ying, *, Yin-,,,,. Deoxyribonucleic acid binding, antitumor activity and complexes of novel deoxyribonucleic acid (IV) with substituted ethylenediamine tetraacetic acid. Bioorganic chemistry Journal, 20 13, 18(8):975-984.
When you smell the incense, you can see the dish, Rong Wei and He, Hai Weiguo and Jia Zhenglu *. Asymmetric vanadyl (Ⅳ) complexes of salicylaldehyde and phenanthroline: synthesis, anticancer activity and antitumor activity. Chemical biology 1030- 1033. (included in SCI)
Jia, Jin, Liang Nianji and others. Porphyrin-fluorescence hybrid supramolecular self-assembly was synthesized by hydrogen bonding. China chemical newsletter 2005:16; 303-306. (included by SCI)
Jia, Jin, Liang Nianji and others. A New Fluorescein-Porphyrin Zinc (Ⅱ) Hybrid: Self-assembly of Porphyrin Manganese (Ⅲ) with imidazole linkage was synthesized through coordination bond. Metal chemistry 2005: 30; 643-649. (included in SCI)
Yun-,Wen-,Jia-(Lu). Illegal effect of ruthenium (Ⅱ) complex binding to DNA. Journal of Chemical Coordination 2009, 62 (04), 665-675 (included by SCI).