It should be understood that antigens are suitable for the human body. If genes with brand-new DNA or RNA genetic material are transported to damaged tissues of human body, antibodies will kill these genes. Therefore, in addition to using CRISPR for gene editing, scientists also have a persistent direction, that is, wrapping the genetic material of DNA or RNA in a shell to protect them from human antibodies, and then expelling these genetic materials from specific damaged human tissues or organs, thus protecting this shell, which is a specific virus.
At present, scientists have developed an AAV. Why is this? Perhaps the appreciation is because the virus is already "toxic". Compared with other viruses that can be used as a protective cover for genetic material. This gene editing method is also being explored at present. Because the integration of retrovirus is random, if the activation of proto-oncogene leads to canceration, its safety will be questioned. Therefore, the search for specific and effective targeted repair tools has attracted much attention in the field of gene therapy.
In any case, the development of gene editing technology is a small breakthrough in medical analysis. Compared with traditional gene therapy methods, gene editing technology is to transform DNA sequences above the genome level, and then repair gene defects or change cell functions, so that malignant diseases such as leukemia, AIDS and hemophilia can be completely cured.