1 Causes of psychological abnormality in hospitalized patients with liver cirrhosis 1. 1 Physiological causes The liver is the most important metabolic organ in human body. The liver function of patients with liver cirrhosis is seriously damaged, and the inactivation of catecholamine by liver is weakened. Catecholamine is one of the main hormones regulating emotional changes, which may lead to abnormal behavior and personality of patients. 1.2 disease has long plagued liver cirrhosis. With the decline of liver function, the symptoms of patients are more prominent. They are often worried about bleeding, hepatic encephalopathy and other symptoms, and some patients are worried about cancer. At present, there is no special treatment for liver cirrhosis in China. Liver cirrhosis is the direct cause of depression and anxiety of patients, especially the sudden events such as death of patients often become malignant stimuli, which leads to the deterioration of patients' mood. These patients pay too much attention to the changes in their condition. Pay attention to the results of each test. 1.3 The role of society and family changes the long-term illness of patients with liver cirrhosis, which makes the patients' work and labor ability decline and seriously affects their career development, family life and marriage quality. Especially for some middle-aged people, it is time to do business and take care of their children. Their social roles are in sharp contrast with their sick roles, which causes great psychological pressure to patients. 1.4 Inferiority At present, a considerable number of people in the society lack understanding of cirrhosis, fear and discriminate against patients, which leads to patients' inferiority complex and interpersonal tension, and some even ask for confidential treatment. These are all important reasons for the symptoms of obsessive-compulsive disorder and hostility. 1.5 Help-seeking psychological patients with liver cirrhosis have a sense of psychological loss due to long-term illness, which leads to an increase in help-seeking psychology. They hope to get care, sympathy and pity from family members, friends and medical staff, but their needs are often unsatisfied because of illness and incomprehension. These factors hurt patients' self-esteem and make them feel lost. 1.6 Heavy economic burden At present, in the medical and health reform system, the increase of medical expenses borne by patients themselves is an important factor that makes patients feel depressed, anxious and hostile. In the survey, 28.3% were self-funded patients, and 63.3% of inpatients raised economic problems as their main hospitalization concerns. 1.7 The psychological influence of gender on patients with liver cirrhosis. The incidence of the disease in men is significantly higher than that in women, and the hostile factors of male patients are also significantly higher than that of female patients. This is related to the social role of men and may be influenced by traditional concepts. Men have greater work pressure than women, while women pay more attention to psychological catharsis. From the clinical observation, these male patients often have a strong sense of alert to their families and medical staff, and some even make things difficult for medical staff, deliberately destroy the public property of the hospital, and fail to implement the hospital's hospitalization rules and regulations. 2. Nursing 2. 1 Comprehensive evaluation of patients. After the patient is admitted to the hospital, the nurse who carries out individualized nursing should comprehensively collect information and evaluate the patient's situation, including discomfort symptoms, occupation, culture, attitude towards the disease, understanding of the disease, family economic conditions, social support system, etc. On the basis of accurate evaluation, make a systematic and effective nursing plan and implement personalized nursing for different individuals. Male patients are obviously hostile, so be patient and persuade them. Patients with serious illness often lose confidence in treating diseases. Nurses should explain to patients the complexity of the process of illness change, and at the same time feedback the information of treatment improvement to patients in time. 2.2 Strengthen nurse-patient communication, establish a good nurse-patient relationship and establish a good trust relationship with patients, actively talk with patients, patiently listen to and answer patients' questions, and often give encouragement and support, so that patients can rebuild their self-confidence and face diseases with an optimistic and positive attitude. In the process of talking with patients, we should correctly use supportive treatment methods such as encouragement, comfort, explanation, guarantee, guidance and suggestion to solve patients' psychological problems and provide patients with psychological support. 2.3 do a good job of family members, get the cooperation of family members, do a good job of protective medical care, and at the same time introduce the illness and treatment to family members in detail to get the cooperation of family members. Ask the patient's family members to encourage and support the patient with a good mood and positive attitude, and tell the family members not to pay attention to the illness during the visit. Family members should understand patients, visit patients more, and don't show boredom and fear. 2.4 Strengthen health education and introduce disease-related knowledge in easy-to-understand language, including pathogenesis, clinical manifestations, usage, dosage and side effects of drugs, precautions for taking drugs, methods for handling adverse reactions, dietotherapy and ways of disease transmission. Make patients change their wrong ideas about diseases, teach patients and their families to implement disinfection and isolation measures, build confidence and actively cooperate with treatment.