Clothing enterprises, as labor-intensive enterprises and key fire prevention units, have many types of work, wide distribution, complex production processes, high utilization rate of mechanical and electrical equipment, and many inflammable and explosive articles, and shoulder very arduous and complicated safety production management work, and the responsibility for safety production is more important than Mount Tai. The author believes that textile and garment enterprises should set up scaffolding, open protective nets and build five lines of defense for safe production in their daily work. The first line: the line of defense of ideological understanding. According to the "Safety Production Law", "Labor Law" and other laws and regulations, formulate perfect labor protection and safety accident handling regulations. Clarify the principle of who bears the responsibility, strengthen the publicity and education of safety production knowledge, improve employees' self-responsibility consciousness and safety production consciousness, and make them build a defense line of self-management and operation in ideological understanding. The second way: the defense line at the work site. This website is the birthplace of potential security risks. Grasping this point, while strictly implementing the systems of fire prevention and explosion prevention, equipment maintenance, flying flowers cleaning and hazard source inspection, we should also rationally allocate equipment, strengthen the management of fixed places, hang (post) safety operation regulations, and prepare warning signs such as shutdown and overhaul. Signs such as prohibition, warning and prompt shall be set in key parts and dangerous areas respectively, especially for the handling, stacking and inventory of inflammable and explosive articles. The third way: the defense line of labor insurance supplies. Based on the principle of combining needs with security, the distribution standard of labor insurance products is formulated, and the decrease will be reduced and the increase will be increased. The focus of distribution will be on production lines and key production posts. Front-line employees are also required to wear work clothes and labor protection articles during working hours. The fourth way: manage the monitoring defense line. There are many warehouses for semi-finished products, finished products, spare parts and raw materials in textile and garment enterprises, and the scope of safety management and monitoring is complex and difficult. Therefore, in addition to establishing the main person in charge of each unit, it is necessary to fully undertake the safety production management and monitoring of this unit, and also strengthen the improvement of working environment and safety and hygiene conditions to provide and create good and safe working conditions for employees. Establish and improve the target responsibility system for safety production, form a three-level linkage safety production guarantee system for companies, branches and teams, and institutionalize, deepen, systematize and network the work of safety production. The fifth way: the defense line of fire control facilities. Set up full-time or amateur fire brigades, and purchase fire engines, fire extinguishers and alarm systems. Conduct simulation drills frequently, invite fire brigade officers and soldiers to give lectures and give on-site guidance, formulate emergency plans, enhance the ability to deal with safety accidents quickly, and ensure the safety of enterprises.