(1) The onset is hidden and the clinical signs are atypical; (2) the condition is serious and the condition is progressing rapidly; (3) Many diseases are related to other organs. Before the onset, 65% of the elderly had serious accompanying diseases, respiratory diseases ranked first, followed by cardiovascular diseases. These accompanying diseases have a great influence on the prognosis, and the mortality rate with or without accompanying diseases is 65438 06% and 7% respectively. 3.2 Timing of operation The mortality rate of conservative treatment of acute cholecystitis in the elderly is high. Once diagnosed, we must strive for early surgery. Mao Jingxi and others [8] think that the only factor affecting the operation of acute cholecystitis is the onset time, and Cheng and others [9] think that the best time for laparoscopic cholecystectomy is 72 h after the onset. Koo et al. [10] also believe that the course of disease is the main factor that determines the success of LC. The author believes that once acute cholecystitis occurs due to factors such as vascular sclerosis in the elderly, the course of the disease progresses rapidly, and the conservative treatment effect is poor, which is easy to cause gallbladder suppuration, pus accumulation, gangrene and perforation, with serious consequences. LC should be performed within 48 ~ 72 h of onset, except for patients whose general condition is too poor to tolerate surgery. At this time, the adhesion between gallbladder and hilum is mostly simple fiber, local edema is not serious, and it is easy to separate from the surrounding adhesion, which can improve the surgical effect, reduce the rate of conversion to laparotomy and the incidence of serious complications, and shorten the postoperative hospitalization time. 3.3 Problems that should be paid attention to during the operation should be shortened as much as possible, the operation should be gentle, ECG monitoring should be strengthened, pneumoperitoneum should be established at low flow rate, and the continuous pneumoperitoneum pressure should not be too high, and it should be controlled at 1.33 ~ 1.60 kPa. Pay attention to prevent subcutaneous emphysema during puncture, and discharge CO2 gas from abdominal cavity after operation. The anesthesia should not be too deep, so as to ensure that the patient can wake up quickly when the operation is completed. [During acute inflammation, the gallbladder is often swollen, congested and edematous, and it adheres to the surrounding area, and the anatomy is unclear. When separating adhesions, first separate the adhesions around the gallbladder, and then separate the adhesions gradually to the junction of the ampulla of the gallbladder and the cystic duct, confirm the ampulla of the gallbladder, dissect the cystic duct, and then track the distal end of the cystic duct, but don't deviate too much to the common bile duct, so as not to damage the common bile duct (liver), which is especially important when the cystic duct is short and thick. When the tension is too high, it is difficult to clamp, which prevents Calot triangle and gallbladder neck tube from being exposed. At this time, decompression can be performed at the bottom of gallbladder, but the decompression amplitude should not be too large, and a certain tension should be maintained, which is beneficial to Calot triangle dissection and gallbladder dissection. If the gallbladder wall thickness and edema are still difficult to grasp, cut at the ampulla of the gallbladder and grasp it in a single layer. In principle, it is better to injure gallbladder than bile duct. In acute inflammation, gallbladder tissue is edematous and fragile, and ossification of cystic duct should be avoided when separating. When clamping the cystic duct with titanium clip, don't use too much force, so as not to clamp part of the cystic duct, which will cause postoperative stump necrosis, shedding and bile leakage. In case of stone impaction in the neck of gallbladder or cystic duct, it is necessary to separate the cystic wall next to the stone impaction in the neck of gallbladder or cystic duct, and then separate the Calot triangle, so as to understand the relationship between cystic duct and common bile duct (liver) or right hepatic duct, and then treat the cystic duct. It's really difficult to dissect Calot triangle. Retrograde, retrograde and antegrade cholecystectomy should be considered. For triangular hemorrhage of gallbladder, don't panic, don't pinch or coagulate at will, so as not to cause damage to the side wall of bile duct or incomplete or complete bile duct atresia and electric burn. The correct treatment is to quickly clamp the bleeding point, clean up the operating field, and ligate after dissection.