The influence of manuscript withdrawal on academic career is various, which depends on the reasons for manuscript withdrawal, the journals of manuscript withdrawal and the academic views on manuscript withdrawal. The following are some possible impacts:

1.** Reputation damage * *: Once an article is retracted, especially in a well-known journal, it may damage the author's academic reputation. Other scholars may question the authenticity of the author's research methods and data.

2.** Career development is blocked * *: In some academic institutions and research fields, articles published in high-impact journals are regarded as the key to promotion and research funding. The rejection of the article may affect the author's career development and fund application.

3.** The cooperation relationship is damaged * *: If the article involves cooperation with other researchers, withdrawing the manuscript may lead to the breakdown or tension of the cooperation relationship.

4.** Difficulty in republishing * *: Some journals or publishers may have reservations about the withdrawn articles, which may make it more difficult for authors to republish.

5.** Psychological pressure * *: For many researchers, withdrawing manuscripts may bring great psychological pressure, leading to anxiety, depression and even depression.

6.** Economic impact * *: In some cases, the withdrawal of the manuscript may cause the author to lose research funds or other economic compensation.

7.** Legal liability * *: In some extreme cases, if the retraction of an article involves serious academic misconduct, such as falsifying data or plagiarism, the author may face legal liability.