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Readability: Nature requires its published papers to be easily understood by readers. This requirement is not so much a question of language or style as a question of organization and expression. The first language of scientists in China is not English, but they are not discriminated against because of the occasional grammatical mistakes in their papers. Nature magazine hopes to publish papers that can reflect the most important scientific research achievements, and its editors are also willing to help authors express their research work in correct English. Many editors of Nature magazine come from non-English speaking countries. For people who are not very proficient in English, the most important thing is to explain their research work in the paper as simply as possible when submitting the manuscript. Novelty: As a weekly magazine, Nature must select research papers whose results contain some novel components. Such a paper can not only describe a previously unknown phenomenon, but also question a previously widely accepted hypothesis. For example, a paper that convincingly proves eternal motion will be given priority by Nature compared with a paper that proves eternal motion impossible. Originality: naturally, priority is given to those novel, unique and ingenious research works, including those that obtain some reliable results through ingenious improvement of very simple paths and methods, and those that skillfully apply knowledge from one field to another. Although not every paper published in Nature should contain all the above elements, they usually must meet more than one of them. Nature magazine does not exclude the publication of highly professional but very important papers, nor does it exclude the publication of papers introducing interesting phenomena that cannot be explained at present. However, due to the limited space, the chances of such papers being hired are relatively small.