1, the formation of gallstones is related to eating habits. For example, I don't like breakfast, because the fasting time is long, which easily leads to high bile concentration in the gallbladder and poor gallbladder contraction function.
2, the westernization of diet, high-fat and high-cholesterol diet, prone to cholesterol supersaturation, leading to changes in bile composition, excessive cholesterol precipitated from bile, thus forming stones.
3. Blood diseases or biliary tract infections lead to the increase of unbound bilirubin in bile, thus promoting the combination of calcium ions with it and forming bile pigment stones?