Jonah hax's violent history and his narrow escape have become legends and mysteries. No one can tell exactly how jonah hex got here, and no one knows what kind of life jonah hex lived. It is this experience that makes jonah hex a mysterious figure who transcends the real world and the surreal world. However, jonah hex is not a lone ranger. He is still connected with human beings. He is closely related to a prostitute named Riley (megan fox).
American soldiers found jonah hex, and they gave him an offer he couldn't refuse. As long as Quentin Turnbull (john malkovich), a voodoo magician, can be eliminated, hax will be free again. Many years ago, Quentin Turnbull killed hax's wife and children and left a scar on his face. This time, hax had a chance for revenge. However, Quentin Turnbull is not such an easy opponent. His men are assembling a death army, eager to kill in America. At the same time, Quentin Turnbull regards hax as his sworn enemy, and he wants to kill hax as soon as possible.