2.TAT-mediated novel intracellular targeted drug delivery system for exciting tumors (first completed) (National 973 Special Fund, 200 1-2003, 200 1CCC0 1400)
3. Study on the Construction of Functional Genes and Drug Supercarriers across Blood-brain Barrier (First Completed Person) (National Natural Science Foundation Project, 2004-2006, 50373033, in cooperation with Tianjin General Hospital)
4. Research on novel gene-targeted controlled-release nano-carrier materials (first completed person) (Project of "2 1 Century National Education Revitalization Plan" of the Ministry of Education, 2000-2003, in cooperation with the University of Michigan, USA)
5. Preparation of Nano Quantum Dots and Research on Detection Technology of Avian Influenza Virus (co-organizer) (key projects of Ministry of Science and Technology, 2006-2007, 2004A519A56-04, in cooperation with Beijing Entry-Exit Inspection and Quarantine Bureau)
6.BD- series multifunctional natural and efficient clarification technology (completed for the first time) (state administration of traditional chinese medicine appraisal project, 1996)
7. Study on compound functional gene delivery system targeting malignant glioma of human brain (the first completed person) (key project of applied basic research of Tianjin Science and Technology Commission in 2005-2008, 05YFJZJC0 1000)
8. Establishment of multifunctional targeted gene delivery system (completed for the first time) (key project of applied basic research of Tianjin Science and Technology Commission in 2005-2007, 05YFJZJC0 100 1)
9. Development of a new drug carrier system with targeted excitation (first completed person) (Key Fund Project of Applied Basic Research of Tianjin Science and Technology Commission, 200 1-2004, 0 136 16 1)
10. research on new targeted therapy carrier system (first completed) (key scientific and technological project of Tianjin science and technology commission, 2002-2005,02311711)
1 1. development of electric release coil for interventional embolization (first completed person) (key scientific and technological project of Tianjin science and technology commission, 1998-200 1 year, 9731133/kloc-)
12. Interventional medical catheter and coil (pilot) (completed for the first time) (key scientific and technological project of Tianjin Science and Technology Commission in 2000-2003, 003112511)
13. Preparation and clinical detection of progesterone immune nanospheres (first completed person) (supported by Tianjin Natural Science Foundation,1996-1999,96360781kloc-0/,in cooperation with Tianjin Central Obstetrics and Gynecology Hospital)
14. Study on compound functional gene delivery system targeting malignant glioma of human brain (first completed person) (Tianjin International Cooperation Fund Project 2005-2007,05 05YFGHHZ20070, in cooperation with University of Michigan, USA)
15. Development of CD4+T lymphocyte absolute counting kit (completed for the first time) (horizontal fund project, 2005-2006, in cooperation with Concord Stem Cell Genetic Engineering Co., Ltd.)
16. development of injectable calcium sulfate nano-repair material (completed for the first time) (horizontal project, in cooperation with Beijing yihuajian science and trade co., ltd., 2006-2009)
17. research on magnetic nano immunodiagnostic reagent (first completed) (horizontal subject, in cooperation with Tianjin Jiuding biotechnology co., ltd., 2004)
18. Amphiphilic compound targeted controlled release nano-drug preparation (co-organizer) (National 863 Key Project, 2007-20 10, 2007AA02 1802, in cooperation with Tianjin Medical University Cancer Hospital)
19. Experimental study on the treatment of acute liver failure by immunomagnetic targeted transplantation of rat bone marrow-derived liver stem cells (co-organizer) (National 973 Project (200 1CB509906), National 863 Major Project (2002A 20505 1), Academy of Military Medical Sciences)
20. Degradable Levonorgestrel Polycaprolactone Implant (co-organizer) (National Key Scientific and Technological Project, in cooperation with China Academy of Medical Sciences, 2004-2006).
2 1. Pre-clinical study of a new intrauterine device-levonorgestrel intrauterine sustained-release system (co-organizer) (National Science and Technology Support Project, 2006-20 10, 2006-103b01,in cooperation with China Academy of Medical Sciences).
22. Research on Magnetic Targeted Thermochemotherapy for Malignant Glioma (co-author) (National Natural Science Foundation Project, 2008-2010,30772245, in cooperation with the First Affiliated Hospital of PLA General Hospital)
23. Research on Key Technologies of Gene Vector Intracellular Tracer (Co-organizer) (Basic Scientific Research Business Project of Central Institute of Public Welfare, 2007-20 10, in cooperation with China Academy of Medical Sciences)
24. Research on Reusable Immunosensor Integrated Microsystems (Co-organizer) (Tianjin Key Project of Applied Basic Research 2007-20/KLOC-0,07 JCZDJC10400, in cooperation with Tianda Electronic Engineering Department)
25. Development of interventional therapy microcatheter (co-organizer) (key scientific and technological research project of Tianjin Science and Technology Commission, 1998-200 1 year, 973 1 133 10, in cooperation with Tianjin Brain Center Hospital)
26. Research on drug-controlled release nano-carrier materials for preventing lens opacification after cataract surgery (co-organizer) (2000-2002 Tianjin Natural Science Foundation Project, 0037027 1 1, in cooperation with Eye Center of Tianjin Medical University)
27. Study on targeted controlled release of vincristine in the treatment of orbital adenoid cystic carcinoma (co-author) (Tianjin Health Bureau project, in cooperation with the Department of Ophthalmology, Second Hospital of Tianjin Medical University, 2007-2008).
28. Study on the inhibition of glioma cell growth by RNA interference hTERT mediated by ultramicro-carriers and its mechanism (co-organizer) (Jiangsu Natural Science Innovative Talents Fund, 2005-2007, BK2004428, in cooperation with Jiangsu Provincial Hospital).
29. Preparation of timothalamine nanoparticles and study on its treatment of glioma (co-organizer) (Medical Science and Technology Development Fund of Jiangsu Provincial Health Department, 2004-2006, in cooperation with Jiangsu Provincial Hospital).
30. Preparation and application of anti-VEGF antibody drug-loaded nanoparticles for gastric cancer (co-organizer) (key scientific and technological research project of Guangzhou Science and Technology Commission, 2003-2005, in cooperation with the Affiliated Hospital of Sun Yat-sen University)
22. Experimental study of EGF nanoparticles in treating diabetic ulcer (co-author) (project of Tianjin Health Bureau, in cooperation with Metabolic Disease Hospital of Tianjin Medical University, 2006-2007) 1. Multifunctional Assembly of Novel Polymer Liposomes and Treatment of Malignant Brain Tumors (Project Leader) (National Natural Science Foundation Project, 2009-2012,5088)
2. Research and development of tumor markers labeled with nano-quantum dots and its detection technology (project leader) (Tianjin Key Support Project 2009-20 12)
3. Research and Development and Application of Biochip for Comprehensive Detection of Major Diseases (co-host) supported by National Science and Technology Program (2008-20 10, 2008BAL52B03, in cooperation with the 94th Hospital of PLA)
4. Study on repairing spinal cord injury with C3 combined with self-activated Schwann cells and bone marrow mesenchymal stem cells mediated by magnetic targeting nanocarriers (co-host) (National Natural Science Foundation Project, 2009-2012,30876203, Department of Orthopaedics, Tianjin General Hospital)
5. Experimental Study on Prevention of Restenosis after Coronary Artery Bypass Grafting by Targeted Gene Ultramicro-carrier System (Co-host) (Project of Tianjin Health Bureau, collaboration of Cardiothoracic Surgery of Tianjin General Hospital, 2007-2009)
6. Study on the treatment of oral periodontitis with drug-loaded nano-sustained-release preparation (co-moderator) (cooperative project between Tianjin Medical University and Stomatological Hospital affiliated to Tianjin Medical University, 2007-2009)
7. Basic research on the application of new nano-anesthetic in painless dental treatment (co-moderator) (National Natural Science Foundation project, 2010-2012,30876203, in cooperation with Stomatological Hospital affiliated to Tianjin Medical University)