Lille and its region are one of the important industrial areas in France. In the past, it was mainly metallurgical and textile industries, but now it has developed into a comprehensive industrial base. Its railway equipment output accounts for 50% of the national total output, electricity output ranks second in the country, printing industry ranks second in the country, and machinery manufacturing industry ranks third in the country. The production base of CHARGEUR Group, the largest textile enterprise in Europe, is located in this area.

The Noel-Calais region is developed in commerce. Auchan Supermarket, one of the largest commercial consortia in France, originated in Lille. The headquarters of France's largest mail-order shopping center group "3 Switzerland" is also located in this city.

Noel-Calais is well-developed in transportation. There are three ports and 464 kilometers of expressway in this area, which can lead to the capitals of seven European countries. Lille Airport is an important international airport.

The foreign trade of Noel-Calais region ranks third in France, second only to Paris region and Rhone-Alpes region. Education in this area is very developed. There are 7 comprehensive universities, 15 engineering university, 6 business schools and 4 high-tech schools in the region. The region has a strong scientific research capacity, with a total of 4000 scientific and technological personnel.