Snake venom is a compound substance mainly composed of protein. Tetrodotoxin (TTX) is a powerful neurotoxin and one of the most toxic non-protein substances found in nature. In fact, it is not secreted by the puffer fish itself. In fact, it is secreted by a tetrodotoxin (TTX；; Protein produced by pseudoalteromonas alternata will be denatured at high temperature, which makes the snake venom lose its toxicity (it is not clear whether all protein toxins will lose their toxicity at high temperature or will not be transformed into other toxic substances). Protein denaturation: Under the action of heat, acid, alkali, heavy metal salts, ultraviolet rays, etc. Protein will change its nature and condense, which is irreversible and cannot be restored to the original protein. This effect is. After denaturation, protein lost its original solubility and physiological function. High temperature can inactivate most of protein, but not alkaloids. It is generally believed that the evolution of snake venom is an accidental result. It is possible that the original form of snake venom is just a powerful digestive enzyme, which can help break down food quickly. However, when the snake gene was copied, there was a mutation, which made the digestive enzyme quickly paralyze the nerves and hearts of animals. Since then, natural selection has made these protein more and more deadly. Tetrodotoxin exists widely in many marine organisms, but its forms are different. It is generally believed that its evolution process is a complex toxin formed by these animals after eating the toxic ladybug Vibrio and conch, which are unique to the ocean, and absorbing the toxic bacteria of these animals and plants.