At the same time, the sperm bank will creatively introduce the evaluation and screening mechanism of sperm donation volunteers in terms of mental health, so as to reduce the possibility of psychological and mental diseases being passed on to future generations through heredity.
Xu Congjian, dean of the Obstetrics and Gynecology Hospital affiliated to Fudan University, pointed out that Fudan University's human sperm bank not only pays attention to the morphology of sperm, but also pays attention to sperm health from the micro-genetic level and macro-psychological level, thus better ensuring male reproduction and healthy human reproduction.
After women are over 35 years old, the quality of eggs decreases rapidly, and the rate of fetal malformation also increases. The number of gene mutations carried by sperm will also increase rapidly with the increase of male age, which greatly threatens the safety of mother and baby and affects the health of future generations. It is reported that at present, the genetic analysis of sperm donors in China is still limited to chromosome detection, while gene mutation screening of common genetic diseases has been popularized abroad. Professor Zhang Feng, deputy director of the State Key Laboratory of Genetic Engineering of Fudan University and head of the human sperm bank of Fudan University, said that genetic screening can control the "internal health" of sperm with higher quality and prevent genetic variation related to major diseases from being transmitted to future generations through sperm to the maximum extent.
It is reported that the human sperm bank of Fudan University will devote itself to a breakthrough at the gene level, and carry out large-scale screening of pathogenic gene loci in sperm of sperm donors among more than 20,000 gene loci currently recognized by human beings. The sperm bank will also use the human phenotype analysis strategy to find new indicators and new "internal health phenotype" for sperm health evaluation, and improve the sperm quality evaluation standard from "external health" to "internal health".
It is known that this innovative task named "Sperm Health Phenotype Analysis" is connected with the "International Human Phenotype Project" and is one of the important contents of the construction of Shanghai Global Science and Technology Innovation Center. Screening at the gene level can control the "internal health" of sperm with higher quality, prevent genetic variation related to major diseases to the maximum extent, and pass it on to future generations through sperm.
Scientific research has confirmed that some mental diseases and mental diseases have genetic risks. At present, sperm banks in China are generally equipped with screening for major mental illness. The human sperm bank of Fudan University will also creatively introduce the evaluation and screening of sperm donors in terms of mental health to ensure the physical and mental health of sperm donors.
It is reported that on the basis of mental health assessment, Fudan University's human sperm bank uses international standard questionnaires and scales to evaluate the psychological characteristics and behaviors of volunteers, such as personality, social skills, brain thinking ability, etc., and gives quantitative values, so as to accurately screen out whether the donor volunteers have mental illness and mental health problems, and reduce the possibility of mental illness and mental illness being passed on to future generations through heredity.