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Professor Jiang Jianhui of Hunan University
outline

Name: Jiang Jianhui.

Gender: male

Political views: Democratic Progressive Party

Date of birth: 197 1. 10.

Highest education: Doctor.

Graduation date: 1999.7

Graduate school and major: Analytical Chemistry, Hunan University.

Title: Professor Evaluation Time: Doctoral Supervisor in 2003

Research interests: chemometrics, chemical biosensor teaching and scientific research.

1999 graduated from Hunan university with a doctorate in analytical chemistry. He used to be a postdoctoral researcher at the Faculty of Science, Kansai University, Japan (200 1. 10-2002。 12), visiting professor (200 1. 1 1-2002。 2)。

His main research interests are chemometrics and chemical sensors. Focusing on the methods and technologies of protein, nucleic acids and small molecules, the molecular basis of biometric identification and the new principle of signal conversion with high sensitivity and high selectivity are explored and solved, and new methods of signal conversion and amplification of various biometric identification are developed, forming a systematic and unique research result. Mainly as follows:

1) put forward a new principle of surface proximity hybridization analysis biosensor, which solved the technical bottleneck of needing conformational change information, difficult design and low sensitivity in aptamer sensing research, and systematically established a new biosensor method for detecting protein, nucleic acids, small molecules and metal ions.

2) A new ligase analysis technique for gene point mutation was established, and a new idea of two-level analysis based on homogeneous identification and surface detection was proposed, which improved the stability and reproducibility of the method and solved the technical bottleneck of high specificity detection of mutants in a large number of wild-type genes.

3) A new biosensor method based on the tunneling current effect of carbon nanotubes is developed, which solves the problem of sensitivity loss caused by the diffusion of electrochemical labeling products in the existing methods; It is the first time to find the terminal protection phenomenon of small molecule modified nucleic acid, develop the biological interaction analysis method of carbon nanotube tunneling current effect label, and then develop a miniaturized micro-gap array sensor device, which provides technical support for the field detection of major diseases. Published more than 60 related international academic papers. He was invited to attend the international conferences of ICAS(200 1, Tokyo) and Interact (Sydney, 2002) and made a special report.