Nucleic acid and protein are the main macromolecules that make up organisms. With the deciphering of the whole genome sequence of a large number of organisms, such as human genome, and the development of functional genomics research, life scientists are paying more and more attention to how to carry out protein genomics research in the mode of genome research. For this reason, Nature and Science published a sketch of the human genome in February, 20001year, and at the same time published comments and prospects on Now for protein Group and protein Genomics in genomeland, respectively, which promoted the status of protein Genomics to an unprecedented height, and thought that protein Genomics would become one of the strategic commanding heights of the biggest strategic resources in the new century-the war of human genes. Although protein's omics has not been published for a long time, it has made a strong exploration in the study of cell proliferation, differentiation, abnormal transformation and tumor formation, involving leukemia, breast cancer, colon cancer, bladder cancer, prostate cancer, lung cancer, renal cancer and neuroblastoma, and identified a number of tumor-related proteins, which provided an important basis for early diagnosis, drug target discovery, curative effect judgment and prognosis of tumors.

In view of the development prospect of protein omics and the importance of advanced technology, the major western developed countries have invested huge sums of money to start the research of protein Group. For example, the National Institutes of Health, the U.S. Department of Energy and the European Energy Research Institute have started the research on different biological protein groups, and made remarkable progress. A number of high-quality research papers have been published in internationally renowned academic journals. Because genomics research in protein is more practical than genomics research and has a huge market prospect, enterprises and pharmaceutical companies have also invested a lot of money in genomics research in protein. Celera, which independently sequenced the human genome, announced that it would invest hundreds of millions of dollars in this field. Protein Group Company and Brock Mass Spectrometer Manufacturing Company jointly established the world's largest protein Group Research Center. In order to promote the development, cooperation and exchange of protein Group in countries and regions, the International Human protein Group (HUPO) was established, the first international protein Group conference was held in France, and corresponding chapters were established in North America, Europe, South Korea and Japan. Protein omics has become a "hot spot" in major western developed countries and multinational pharmaceutical groups.