If a major scientific discovery is published, no institution will accept it because the publication of a major scientific discovery is only the first step. After the paper is published, if it is an important discovery, many laboratories will follow it up. Only when the same result can be repeated can the discovery be established (if other laboratories cannot repeat the same result, the publisher of the paper will be required to provide complete experimental data, which is the rule of international academic circles. According to the experimental data, it is possible to get the result of the paper, which may belong to the falsification of the paper.
Once scientific discovery is established, international academic circles and professional committees will make this important discovery public, and it may be written into textbooks by various countries and recommended as candidates for Nobel related awards.
When you say acceptance, you should mean acceptance after the application for a patent for science and technology, which belongs to the patent office.