2. Bao was discovered by Hench at 1969. It is a silicate glass composed of basic components such as SiO2, Na2O, CaO and P2O5. The degradation products of bioactive glass can promote the production of growth factors, promote cell proliferation, enhance the gene expression of osteoblasts and the growth of bone tissue. It is the only artificial biomaterial that can be combined with bone tissue and connected with soft tissue.