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With the rapid development of computer and automatic measurement technology, reverse engineering has become a technical means to use computer technology to simulate products and develop new products. At present, reverse engineering technology has been combined with advanced manufacturing technologies such as CAD/CAM, and has developed into a relatively independent research field in CAD/CAM system. The application of reverse engineering in injection mold design is a new development direction of injection mold design. It takes modeling entity as the research object, uses advanced measurement technology and self-checking software to reconstruct the curved surface, and designs products on the basis of the curved surface. This design method can flexibly adapt to plastic products with complex curved surfaces, and greatly meet people's needs for product appearance except product structure. Taking the watch case as an example, this paper mainly introduces the application of reverse engineering in mold design and the design process of injection mold. The data of solid point cloud is measured by three-dimensional coordinate non-contact laser measuring instrument, and the surface of the point cloud is reconstructed by using advanced Pro/E three-dimensional design software. Based on the curved surface of heavy building, the product structure is designed. Design the corresponding injection mold according to the product structure. Among them, the design of injection mold includes: molding model analysis, parting determination, cavity and runner layout, gating system design, cold material science and hook drawing device design, exhaust system design, structure and size design of injection mold working parts, mold closing guide mechanism design, lifting mechanism design, temperature control system design, etc.