On June 5th, 2002 1,1,according to the data released by National Health Commission, COVID-19, China Province had more than 900 million doses of vaccination, covering more than 600 million people, ranking first in the world in terms of vaccination times and population coverage.
The general process and cycle of vaccine research and development includes two stages:
The first stage is the pre-research and development of vaccine, including obtaining immunogen (obtaining live virus, separating related subunits, obtaining recombinant protein or synthesizing related DNA(RNA) through gene recombination technology, immune response test, animal protection test, optimization of immunogen production process (amplification), preclinical toxicology research and so on.
The second stage is the process of vaccine development and registration, including pre-clinical research, clinical application and clinical trials, and finally the vaccine can be listed. ?