The combination of traditional Chinese and western medicine is very common in rural areas and cities in China, and has become the routine of clinical medication in many primary hospitals. According to the statistics of Beijing Hospital of Traditional Chinese Medicine, the patients in this hospital 13.63% are mainly decoction and western medicine. 24.7% of Chinese patent medicine patients are mainly Chinese patent medicine patients. 57.34% of western medicine patients are mainly treated with western medicine and Chinese patent medicine. Many cities, especially medical units at or below the county level, have higher rates. The reason is generally believed that Chinese medicine is mild and safe, and the combination with western medicine can enhance the curative effect; Some patients are anxious to get better, see Chinese medicine and western medicine; Some doctors seek stability, and the more drugs they use, the better. These are the main factors in the integration of traditional Chinese and western medicine at present. However, the key lies in how to carry out in-depth clinical and experimental research on the combination of Chinese and western medicine, foster strengths and avoid weaknesses, and use Chinese and western medicine economically, safely and effectively, which will be a research topic suitable for China's national conditions and with broad prospects.
Traditional Chinese medicine has been used in China for thousands of years, and accumulated extremely rich knowledge of drug action. The whole history of the emergence, enrichment and development of traditional Chinese medicine shows that its main contents, such as the generation of drugs, the theory of medication, and the choice of drugs, all reflect the holistic idea of combined medicine. The combination of traditional Chinese medicine emphasizes syndrome differentiation and treatment, and the drugs in a prescription constitute an organic whole, rather than simply prescribing the right medicine. In recent years, great progress has been made in the pharmacological research of single Chinese medicine in China, but it cannot be separated from or replaced by traditional Chinese medicine theory and syndrome differentiation. The use of western medicine focuses on the relationship between symptoms and effects, however, the objective situation is not so simple. If cough is the common symptom, Kebiqing and codeine are selected, but clinicians often choose Chinese patent medicines such as Chuanbei loquat dew, Tankejing, Sydney ointment and Keteling, or use decoction. Because Chinese medicine treats cough as a disease in internal medicine, there are two categories: exogenous diseases and internal injuries. Exogenous diseases are different from cold and heat, and internal injuries are different from lung deficiency, phlegm-dampness and liver fire. Therefore, corresponding prescriptions are also selected for treatment, which is always based on syndrome differentiation.
Visceral imaging laboratory of Shanghai Medical University found from animal experiments that drugs for warming kidney and benefiting Yang Can protected adrenal gland from the inhibition of exogenous sex hormones, but after blindly applying this result to clinic, problems were found. This is because after long-term clinical use of large doses of hormones, there will be blushing, insomnia, anxiety, and excessive internal heat. If you add hot medicine to warm and tonify kidney yang, it is tantamount to adding fuel to the fire. According to the theory of traditional Chinese medicine, deficiency-heat syndrome caused by high-dose hormone can be treated with Dabuyin Pill, so the experimental scheme was redesigned and Radix Rehmanniae, Rhizoma Anemarrhenae and Radix Glycyrrhizae were selected. 14 adult nephrotic syndrome patients, 30 ~ 40mg/ day of prednisone combined with the above traditional Chinese medicine does not affect the curative effect of unfair hormones, and the side effects are reduced. Later, the feedback internal inhibition experiment of nourishing yin and reducing fire with supervised hormones confirmed that the combination of Radix Rehmanniae, Rhizoma Anemarrhenae and Radix Glycyrrhizae all had antagonistic endogenous inhibition, with Rhizoma Anemarrhenae being the strongest, while for long-term low-dose hormones and hormone reduction, it was mainly combined with traditional Chinese medicine for warming kidney and strengthening yang. But the final choice is still based on the "syndrome differentiation" of traditional Chinese medicine. This fully shows that the combination of traditional Chinese and western medicine must follow its own theory, not simply adding up, let alone piling up drugs. The reasonable compatibility of Chinese and western medicine depends on a large number of pharmacological experiments, but at present it is more directly used in clinic. Therefore, it is very important to study the law of the combination of Chinese and western medicine and its incompatibility from the perspective of pharmacology, chemistry, biology and Chinese medicine theory.
It is worth noting that foreign countries have also attached importance to the integration of traditional Chinese and western medicine. The famous Japanese traditional Chinese medicine temple Ze Jienian made a comprehensive report on the present situation of a large number of integrated traditional Chinese and western medicine. For example, Japanese cold medicine "ガゼ" No.5 (Pinellia ternata, Magnolia officinalis extract, paracetamol, caffeine). In Japan, glycyrrhizin, cysteine and glycine are dissolved in physiological saline for clinical antiallergic and antidotes. The combination of Shiquan Dabu Decoction and chemotherapy drugs such as azithromycin C and cisplatin can enhance the anti-tumor activity of drugs and reduce the toxic and side effects of chemotherapy. What is particularly commendable is that in recent years, Japanese traditional Chinese medicine has conducted many experimental studies on the integration of traditional Chinese and western medicine. For example, Sakata confirmed that the combination of glucocorticoid and saikosaponin A can enhance the anti-granulomatous effect of steroids; The combination of saikosaponin B and glucocorticoid can inhibit the increase of triglyceride in blood caused by steroids, and the activities of various enzymes in liver are also increased by the combination of saikosaponin. The study of inflammation model in Yukio Dihara rats found that Xiaochaihu decoction combined with prednisone can significantly reduce adrenal atrophy and improve leukopenia caused by anabolic steroids. Similar reports involve the combination of traditional Chinese medicine prescriptions and various Xizang Autonomous Region drugs, which will be of great help to the combination of traditional Chinese medicine and western medicine, which has been widely used in clinic. Looking at the present situation of the combination of traditional Chinese and western medicine, on the one hand, the combination of traditional Chinese and western medicine has improved the curative effect and shortened the course of disease, and its application probability is getting higher and higher, which is gradually accepted by the masses. There are more and more reports on its application rules and taboos, which shows that the combination of traditional Chinese and western medicine is attracting the attention and research of the majority of medical workers. On the other hand, blind use, two-pronged, no taboo, resulting in waste and even drug-induced diseases are increasing. Therefore, the study of the interaction between Chinese and Western medicine is not only of far-reaching academic significance, but also of great practical significance.