Because we know that the secretion of calcitonin is related to the calcium concentration in blood flowing through the thyroid gland, and in severe pancreatitis, the calcium concentration in blood decreases due to the saponification of fatty acids and blood calcium. It stands to reason that calcitonin secreted by thyroid gland should compensate for the decrease of blood calcium concentration, but why should it be reduced?
In fact, there is no clear answer to this question in the medical field, but in recent years, many related frontier experiments and studies have been carried out around this core issue.
Previous studies have shown that pancreatic α cells stimulated to secrete glucagon in acute pancreatitis can make thyroid secrete calcitonin and inhibit calcium from being released from bone, leading to fat necrosis and calcium depletion in pancreatitis.
However, another recent experiment found that injecting glucagon into normal people did not cause hypocalcemia. Therefore, some people think that the reason of low calcium is that parathyroid hormone is decomposed by protease and cannot maintain the level of calcium.
At the same time, procalcitonin (PCT) has been paid more and more attention in recent years, and it is considered as an important indicator of severe bacterial infection with systemic inflammatory response. Procalcitonin is a propeptide of calcitonin. Under normal circumstances, PCT is produced by thyroid C cells. In the blood of healthy people, PCT (
Yes, when rescuing patients, we should grasp the key points and rescue them in time, and don't care too much about some details. However, when studying, we must grasp the theory in a down-to-earth manner and gain a profound and comprehensive understanding, so as to achieve mastery in practical operation. For the contradictions and puzzles encountered in learning, students should bravely ask questions and questions. And our teacher should also encourage students to have this attitude, patiently help sort out the answers, or discuss and study with students. Only in this way can our science make continuous progress and correct the shortcomings and fallacies of our predecessors. If every teacher scolds students for "spending energy on things worth studying in the future" in front of problems that students don't know much about or usually don't pay much attention to, do students have to find out "Teacher, what do you think is worth studying?"
No wonder, our education is always cultivating pseudo-scholars and pseudo-experts who don't know how to think independently but only know how to read and feel. . .